Dual Antiplatelet Therapy Role in Acute Ischemic Stroke

Authors

  • Marjan Assef University of North Carolina at Greensboro, Joint School of Nanoscience and Nano Engineering, North Carolina, USA Author
  • Ayesha Liaquat Karachi Medical and Dental College, Karachi, Pakistan Author
  • Tejal Parmar Vydehi Institute of Medical Sciences and Research Centre, Banglore, India Author
  • Sonam LNU Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan Author
  • Sigmone Fatima Jinnah Medical College, Lahore, Pakistan Author
  • Roohi Khan Rajiv Gandhi University of Health Sciences, India Author
  • Zeynab Salehpour Clinical Research Development Unit Beheshti Haspital, Yasuj University of Medical Sciences, Yasuj, Iran Author
  • Zain Abdin MD, Premier Physicians Delaware, USA Author

DOI:

https://doi.org/10.47363/JCCEM/2023(2)117

Keywords:

Antiplatelet Therapy, Acute Ischemic Stroke

Abstract

Stroke is the second greatest cause of mortality and one of the top causes of long-term disability. The fatality rate and age-adjusted prevalence of stroke have decreased globally over the past quarter-century. However, the absolute number of stroke cases has climbed, as populations have grown older. Initiating antiplatelet medications early in patients with acute ischemic stroke (AIS) is essential for preventing stroke recurrence. Aspirin, clopidogrel, and dipyridamole are the most commonly used antiplatelet medications worldwide. Combining antiplatelet drugs is associated with an increased risk of bleeding when used for long-term prophylaxis. The use of Dual antiplatelet treatment (DAPT) for a shorter duration is associated with a lower risk than long-term usage. The best period of treatment for transient ischemic attack (TIA) and mild ischemic stroke appears to be between 21 and 30 days.

Author Biographies

  • Marjan Assef, University of North Carolina at Greensboro, Joint School of Nanoscience and Nano Engineering, North Carolina, USA

    Marjan Assefi, University of North Carolina at Greensboro, Joint School of Nanoscience and Nano Engineering, North Carolina, USA

  • Ayesha Liaquat, Karachi Medical and Dental College, Karachi, Pakistan

    Karachi Medical and Dental College, Karachi, Pakistan.

  • Tejal Parmar, Vydehi Institute of Medical Sciences and Research Centre, Banglore, India

    Vydehi Institute of Medical Sciences and Research Centre, Banglore, India.

  • Sonam LNU, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

    Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

  • Sigmone, Fatima Jinnah Medical College, Lahore, Pakistan

    Fatima Jinnah Medical College, Lahore, Pakistan.

  • Roohi Khan, Rajiv Gandhi University of Health Sciences, India

    Rajiv Gandhi University of Health Sciences, India.

  • Zeynab Salehpour, Clinical Research Development Unit Beheshti Haspital, Yasuj University of Medical Sciences, Yasuj, Iran

    Clinical Research Development Unit Beheshti Haspital, Yasuj University of Medical Sciences, Yasuj, Iran.

  • Zain Abdin, MD, Premier Physicians Delaware, USA

    MD, Premier Physicians Delaware, USA.

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Published

2023-01-18

Issue

Vol. 2 No. 1 (2023): Volume 2 Issue 1

Section

Articles