Authors
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Adel Hassan Mohamed Hassan
Radiation oncology Department, Maadi Armed forces Medical compound, cairo, Egypt.
Author
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Tarek Huissen kamel
Professor of Clinical Oncologyand Nuclear Medicine, Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Author
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Nesreen Ahmed Mosalam
Assist.Professor of Clinical Oncology and Nuclear Medicine. Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Author
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Sherif Hasanein Ahmed
Lecturer of Clinical Oncology and Nuclear Medicine.Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Author
Keywords:
Prostate-Specific Antigen, Digital Rectal Examination
Abstract
Background: The most common non-cutaneous malignancy for men is Prostate cancer (PCa). PCa diagnosed by biopsy and PSA detection. Bone metastasis (BM) causes a lot of complications, such as bone pain and pathological fracture that cause overall compromised quality of life. Bone scintigraphy (BS) is commonly used for monitoring and detection of (BM).
Objective: To correlate between serum PSA level and BM in PCa patients on series of 250 patients through detecting PSA levels and BSs. Patients and Methods: In the present study Patients were stratified (group A) & (group B) according to BM. Out of the 250 patients, 180 patients (Group A localized PCa) were with age range from 57 -92 years, the remaining 70 patients (Group B metastasis PCa) the age range was 53-88 years. Prostate specific antigen (PSA) level for both groups were detected.
Results: By comparing group A and group B there was a highly significant difference in PSA value in favor of positive BS group (p-value < 0.001). The present study recommends BS in asymptomatic patients with PSA above 60 Ng/ml.
Conclusion: PCa is the most common malignant non-cutaneous tumor for men. The most common spread for PCa is bone spread. Age doesn’t correlate with BM in PCa patients. PSA total show highly significance with BM in PCa patients. PSA cut-off value for BM in PCa patients was 60 Ng/ml so it was recommended to perform BS for asymptomatic patients with PSA total above 60 Ng/ml.
Author Biographies
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Adel Hassan Mohamed Hassan, Radiation oncology Department, Maadi Armed forces Medical compound, cairo, Egypt.
Adel Hassan Mohamed Hassan, Radiation oncology Department, Maadi Armed forces Medical compound, cairo, Egypt.
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Tarek Huissen kamel, Professor of Clinical Oncologyand Nuclear Medicine, Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Tarek Huissen Kamel, Professor of Clinical Oncologyand Nuclear Medicine, Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
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Nesreen Ahmed Mosalam, Assist.Professor of Clinical Oncology and Nuclear Medicine. Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Nesreen Ahmed Mosalam, Assist.Professor of Clinical Oncology and Nuclear Medicine. Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
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Sherif Hasanein Ahmed, Lecturer of Clinical Oncology and Nuclear Medicine.Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
Sherif Hasanein Ahmed, Lecturer of Clinical Oncology and Nuclear Medicine.Clinical Oncology and Nuclear Medicine Department. Faculty of Medicine-Ain Shams University, Egypt.
