Mediastinal PEComa with TFE3 Rearrangement: An Unusual Finding

Authors

  • Hanae Ben Abdenbi Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco Author
  • Fouad Zouaidia Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco Author

DOI:

https://doi.org/10.47363/JCIR/2025(4)143

Keywords:

Mediastinal, PEComa, TFE3 Rearrangement

Abstract

Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms classified by the World Health Organization (WHO) as tumors of uncertain differentiation. They are composed of perivascular epithelioid cells (PECs), which are characterized by their distinctive morphology, close association with blood vessel walls, and dual expression of melanocytic and smooth muscle markers [1].

Author Biographies

  • Hanae Ben Abdenbi, Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco

    Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco

  • Fouad Zouaidia, Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco

    Department of Pathology, Ibn Sina Hospital Center, Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Rabat, Morocco 

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Published

2025-09-05

Issue

Vol. 4 No. 2 (2025): Volume 4 Issue 2

Section

Articles