Trends about Cerebral Syphilis in a 31 Young Patient: A Case Study with Cerebral Perfusion (Spect)

Authors

  • Sebastião David Santos-Filho Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil. Author
  • Roberto Levi Cavalcanti Jales Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil. Author
  • Regina Dantas Jales Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil. Author

DOI:

https://doi.org/10.47363/JCCEM/2022(1)105

Keywords:

Cerebral syphilis, Gama Camera, Nuclear Medicine, HMPAO, Technetium-99m, Psychiatry

Abstract

The cerebral syphilis (CS) became occasional because the detection and to the treatment of the disease in its initial phase. It not disappeared and still present in our days. It is priority to consider the solicitude of syphilis serological reactions in diverse manifestations. Now the use of a Gama Camera to obtain images with Nuclear Medicine probes begin a new era in diagnoses about this disease. With a data bank of images obtained in patients committed with this ill it is be possible to reach a good diagnostic and a good following of the patients. In this work we present a clinical case of a patient 31 years old that have cerebral syphilis showing alterations in brain nuclear medicine images that were useful to make a diagnostic of the disease. The images were obtained with a two-head Gama Camera used with the HMPAO binding with 20mCi of Technetium-99m by endogenous injection, they were made tomographic and tridimensional images. It was seen a significant area with hypo perfusion in topography bi-parietal of the cingulate and superior and inferior faces of the brain, with symmetrical character. The base nucleus (caudate and thalamus) was showed in hyper-perfusion. The rutinary exam of cerebral SPECT with HMPAO revealed a significantly perfusion area and the need of complementary image exams, that evaluated to the final diagnostic of tertiary syphilis. It was evidenced the clinical importance of investigate routineer the cerebral SPECT in patients coming of the psychiatry

Author Biographies

  • Sebastião David Santos-Filho, Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil.

    Sebastião David Santos-Filho, Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil.

  • Roberto Levi Cavalcanti Jales, Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil.

    Roberto Levi Cavalcanti Jales, Clínica Nuclear de Natal, Tirol, Natal, RN, Brasil.

  • Regina Dantas Jales, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.

     Regina Dantas Jales, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.

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Published

2025-12-04