Cardiac Arrest Pregnancy and Amniotic Fluid Embolism

Abstract

Amniotic fluid embolism remains one of the most devastating conditions in obstetric practice with an incidence of approximately 1 in 40,000 deliveries and a reported mortality rate ranging from 20% to 60%. The pathophysiology involves an abnormal maternal response to fetal tissue exposure associated with breaches of the maternal-fetal physiologic barrier during parturition. This abnormal response triggers a cascade of events similar to the systemic
inflammatory response syndrome, involving the activation of proinflammatory mediators. Maternal treatment in cases of cardiopulmonary arrest is mainly supportive, focusing on resuscitation efforts and stabilizing the mother’s condition. However, it is crucial to prioritize prompt delivery in order to improve the newborn’s outcome