A Potentially Fatal Reaction to Dipyrone: Should we Continue Using it?

Abstract

Perioperative anaphylaxis is a severe systemic allergic reaction that can endanger the lives of patients undergoing surgical procedures. It is characterized by an exaggerated immune response to a substance previously recognized by the immune system, leading to the release of vasoactive mediators and other inflammatory compounds. Although its incidence is relatively low, perioperative anaphylaxis is an event that demands immediate diagnosis and treatment to prevent potentially fatal complications [1-4].