Sympathetic Crashing Acute Pulmonary Edema (SCAPE): A Race Against Time in the Emergency Department

Authors

  • Esam Amer Clinical Lead, Emergency Medicine, East Suffolk and North Essex NHS Foundation Trust, United Kingdom Author

DOI:

https://doi.org/10.47363/JCCEM/2025(4)180

Keywords:

Sympathetic Crashing Acute Pulmonary Edema (SCAPE), Nitroglycerin (NTG), High Dose NTG, Non-Invasive Ventilation, Acute Heart Failure

Abstract

Sympathetic Crashing Acute Pulmonary Edema (SCAPE) represents the extreme end of the heart failure spectrum, characterised by hemodynamic instability and severe respiratory distress. Prompt recognition and intervention are crucial to reducing morbidity and mortality in patients with SCAPE. High-Dose Nitroglycerin (HDN) and Non-Invasive Ventilation (NIV) are pivotal in managing these cases. We present a case of a 56-year-old man who presented to our Emergency Department (ED) with SCAPE. He was successfully managed with HDN at a dosage of 100 µg/min and positive pressure ventilation. This case underscores the importance of early recognition and aggressive intervention in SCAPE, highlighting the effectiveness of HDN and NIV in stabilising hemodynamics and improving outcomes. 

Author Biography

  • Esam Amer, Clinical Lead, Emergency Medicine, East Suffolk and North Essex NHS Foundation Trust, United Kingdom

    Esam Amer, Clinical Lead, Emergency Medicine, East Suffolk and North Essex NHS Foundation Trust, United Kingdom.

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Published

2025-10-08