Lyell-Like Acute Graft-Versus-Host-Disease

Authors

  • Caroline de Lorenzi Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland Author
  • Yassaman Alipour Tehrany Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland Author
  • Sébastien Menzinger Division of Clinical Pathology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland Author

DOI:

https://doi.org/10.47363/JDMRS/2021(2)131

Keywords:

Graft-Versus, Disease, Host

Abstract

Stage IV acute cutaneous graft-versus-host-disease (GVHD) is nowadays rarely seen due to tissue typing done before transplant. The first line treatment for acute GVHD grade II-IV is systemic corticosteroids. However, although there is no consensus for refractory cases, literature report diverse therapies to be effective. We report the case of a 34 year-old patient with refractory acute cutaneous graft-versus-host-disease stage IV successfully treated with etanercept.

Author Biographies

  • Caroline de Lorenzi, Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland

    Caroline de Lorenzi. Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland,

  • Yassaman Alipour Tehrany , Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland

    Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland 

  • Sébastien Menzinger , Division of Clinical Pathology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland

    Division of Clinical Pathology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland

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Published

2021-08-15