Chinese Medicine Treatment for Cannabis Drug Abuse --- AnEarly Exploration

Abstract

Background: Being one of the freely used psychoactive substances worldwide, cannabis has not only undeniable addictive effects, but may also leads to cognitive impairments and risks of mental disturbances. To date, there is yet no effective agent for treating cannabis abuse disorders. Traditional Chinese medicine intervention may provide opportunities to alleviate withdrawal symptoms and improve the miserable quality of life.

Methods: 50 eligible cannabis users were recruited on voluntary basis for a clinical trial using Chinese Medicine for a period of 14+14 days. Assessments included Quality of life (SF-36), Hospital Anxiety and Depression Scale (HADS), Patient Health Questionnaire (PHQ-9). Cannabis consumption were evaluated before treatment (visit 1), during treatment (visit 2), extend treatment (visit 3), and post treatment (visit 4). 15 with good compliance was put on an extended course of treatment.

Results: The average age of participants was 23.3 years, with the youngest being 14 years and oldest 47 years. After taking the herbal medicine, both the total participants and subgroups experienced an over 60 percent reduction in the consumption of cannabis (p<0.001). Anxiety (HADS) and mental health (PHQ-9, SF-36) states were improved.

Conclusion: The study herbal formula might be beneficial for cannabis abusers determined to withdraw. Their anxiety and mental health improved. Their craving for cannabis decreased.