Proposal of Pseudo Amino Acid Composition and Its Impacts and Profound Influence

Abstract

In order to take into account the information of biological sequences as far as possible, the paper entitled “Prediction of protein cellular attributes using pseudo amino acid composition” has been published about 11 years ago and its Impacts and profound influence has been very remarkable [1]. See, e.g., [2-16]. Also, before 2001 the support-vector machines (SVMs) had been widely used to classify biological sequences. But it is impossible to use discrete vectors to represent sequences without losing sequence order.