Use of Letrozole in Ovarian Stimulation in Vitro Fertilization

Authors

  • Eduardo Carvalho de Arruda Veiga GERA Institute for Teaching and Research in Reproductive Medicine of São Paulo, Brazil. Author
  • Marcelo Luis Pierro Saraiva GERA Institute for Teaching and Research in Reproductive Medicine in São Paulo, Brazil Author
  • Marise Samama Department of Gynecology, Paulista School of Medicine, Federal University of São Paulo, Brazil Author
  • Fabio Ikeda GERA Institute for Teaching and Research in Reproductive Medicine in São Paulo, Brazil Author
  • Rita de Cassio de Camargo Preto Piscopo GERA Institute for Teaching and Research in Reproductive Medicine in São Paulo, Brazil Author
  • Jarmy-Di Bella S GERA Institute for Teaching and Research in Reproductive Medicine in São Paulo, Brazil Author
  • Joji Ueno GERA Institute for Teaching and Research in Reproductive Medicine in São Paulo, Brazil Author

Keywords:

Letrozole, Gonadotropins, Ovarian Stimulation in Vitro Fertilization, Assisted Reproductive

Abstract

Background: Letrozole is a medication that alone or combined with clomiphene citrate has been used for ovarian stimulation in women undergoing IVF. The objective of this narrative review is to investigate in the recent literature what are the main findings related to the use of letrozole in ovarian induction in human reproduction.

Methods: The search strategy was to use the keywords letrozole and ovarian stimulation and in vitro fertilization in the PubMed database in the last five
years in free-text articles.
•     Results-62 articles were found that applying the eligibility criteria were selected for this narrative review 12 articles.
•     Results-The main findings of this study include information about the author, year, country, study design, number of participants, and more findings of each of the papers selected for this narrative review. 

Conclusion: Although letrozole is a low-cost and safe medication for women, widely used in ovarian stimulation with benefits in endometrial receptivity, clinical results such as pregnancy rate and a number of live births still need large randomized trial studies.

Author Biography

  • Eduardo Carvalho de Arruda Veiga, GERA Institute for Teaching and Research in Reproductive Medicine of São Paulo, Brazil.

    Eduardo Carvalho de Arruda Veiga, GERA Institute for Teaching and Research in Reproductive Medicine of São Paulo, Brazil.

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Published

2024-04-23

Issue

Vol. 6 No. 4 (2024): Volume 6, Issue 4

Section

Articles