Gestational Trophoblastic Choriocarcinoma with Lung Metastasis:A Case Report

Abstract

Background: The choriocarcinomais rare highly aggressive malignant tumor of gestational trophoblastic neoplasia with increasing rate of hematogenous spread to distant organ particularly to the lung. The mortality rate of chroiocarcinoma before chemotherapy management was 90% but advanced chemotherapy approach had contributed to favorable prognostic outcome and more than 90% curative rate.

Aim of the Study: To demonstrate the presentation of gestational trophoblastic choriocarcinoma with lung metastasis and related management outcomes.

Methods and Patient: This study was a case report of gestational trophoblastic choriocarcinoma with lung metastasis which had reported at obstetrics and gynecology department of Tripoli university hospital on 9th December 2023.The patient was on strict clinical and laboratory evaluation and she had received six cycles of chemotherapy management (EMACO) which ended by complete clinical and laboratory improvement.

Comment: Gestational choriocarcinoma is considered as highly aggressive gestational trophoblastic neoplasm with higher liability rate of hematogenous spread particularly to the lung. But with early recognition of the disease as well as prompt chemotherapy management and strict follow up, this contributed to good prognostic outcomes and helps to prevent related morbidity and mortality