Preliminary Assessment of Triglyceride/High-Density Lipoprotein Cholesterol (tg/hdl-c) Ratio among Nigerian Adolescents with Self-Reported Symptoms of Cardiovascular Illness

Authors

  • Susan A Holdbrooke Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria. Author
  • Bamgboye M Afolabi Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria. Author

DOI:

https://doi.org/10.47363/JJCMR/2025(5)188

Keywords:

Cardiovascular Disease, Cerebrovascular Disease, Coronary Artery Disease, Peripheral Artery Disease, Risk Marker, Triglyceride/High-Density Lipoprotein-c Ratio

Abstract

Summary: The need to identify high risk features of atherosclerotic cardiovascular disease (ASCVD) in indigenous Black African adolescents is urgent now more than ever. In ASCVD, an immunoinflammatory pathology, plaques of lipid origin progressively gather in wall of human blood vessels and partially or completely obscure the lumen.

Objective: To determine the association of TG/HDL-c ratio with hypertension and dysglycaemia among apparently healthy Nigerian adolescents.

Materials and Method: A nutritional survey was conducted from October 2019 to March 2010 among secondary school students in Lagos, Nigeria. Statistical analysis was restricted to 613 study subjects whose anthropometric and clinical data were complete. Subjects were categorized into early, mid and late adolescents. A semi-structured questionnaire instrument was used to gather socio-demographic data and information on current health status of the study subjects. Fasting blood was collected for the analyses of plasma glucose (FPG), triglyceride (TG), total cholesterol (T-Chol), high density lipoproteincholesterol and low-density lipoprotein cholesterol. Anthropometric data were also collected. Systolic and diastolic blood pressures were measured.

Author Biographies

  • Susan A Holdbrooke, Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria.

    Susan A Holdbrooke, Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria.

  • Bamgboye M Afolabi, Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria.

    Bamgboye M Afolabi, Department of Biochemistry and Nutrition, Nigerian Institute of Medical Research, 6 Edmond Crescent, Yaba, Lagos, Nigeria.

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Published

2025-03-10