Brine-Shrimp Lethality Bioassay of Different Extracts of the Medicinal Plant Matricaria (Chamomilla) Flowers

Authors

  • Amal Elnour Ali Pharmacist, Omdurman Hospital Author
  • Shayob Mohammed El Hassan Ali University of Khartoum, Faculty of Pharmacy Author
  • Suad Abd Elgadir Abdo EL-Rhman Alzaiem Alazhari University, Faculty of Education, Department of Chemistry Author
  • Mona Abd ELmoneim Mohamed Department of Pharmacognosy, in Omdurman Islamic University Author
  • Tarig Osman khider University of Bahri Author

DOI:

https://doi.org/10.47363/JMHC/2022(4)217

Keywords:

Medicinal Plants, Matricaria, Babonj, Brine Shrimps, Cytotoxicity

Abstract

Objective: The present study aimed to throw some light on phytochemical constituents of Matricaria (cammomile) flowers.

Results: The 95% ethanolic crude extract was subjected to column chromatography and nine fractions were collected. Fractions 1-6 have the same Rf value, (using thin layer pre-coated silica gel (0.25cm). were combined and subjected to spectroscopic analysis; infrared spectra showed absorption at 1860, 1637 and 805 cm’ indicating the presence of c=o, c=c, and c-o groups respectively. Ultra violet absorption at 250-283nm assign for the presence of flavonoids, (lit. 250-280). Finally GC/MS spectra performed the presence flavonoids.Crude extracts (ethanol, methanol, petroleum ether, and chloroform) were investigated for antimicrobial activities against four strains of bacteria (Staphylococcus aureus, Escherichia coli, Bacillus sub tills, Pseudomonas aeruginosa, and two fungi: Asperigillus niger, and Candida albican) with disc diffusion method, the diameter of growth inhibition zone ranged 15-22mm.

Author Biographies

  • Amal Elnour Ali, Pharmacist, Omdurman Hospital

    Pharmacist, Omdurman Hospital

  • Shayob Mohammed El Hassan Ali, University of Khartoum, Faculty of Pharmacy

    University of Khartoum, Faculty of Pharmacy

  • Suad Abd Elgadir Abdo EL-Rhman, Alzaiem Alazhari University, Faculty of Education, Department of Chemistry

    Alzaiem Alazhari University, Faculty of Education, Department of Chemistry

  • Mona Abd ELmoneim Mohamed, Department of Pharmacognosy, in Omdurman Islamic University

    Department of Pharmacognosy, in Omdurman Islamic University

  • Tarig Osman khider, University of Bahri

    University of Bahri

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Published

2022-12-13

Issue

Vol. 4 No. 6 (2022): Volume 4 Issue 6

Section

Articles