Prophylactic Intravenous Hydration Mitigates Postoperative Hypotony and Prevents Choroidal Detachment After Trabeculectomy:A Prospective Case Series

Abstract

Objectives: Choroidal detachment is a common and potentially serious complication following trabeculectomy, often associated with postoperative hypotony. This prospective case series investigated the efficacy of prophylactic intravenous hydration in reducing the incidence of choroidal detachment and mitigating hypotony after trabeculectomy.

Methods: Fifty patients undergoing trabeculectomy, of these 20 (40%) were male and 30 (60%) were female. The mean age at presentation was 66.15 years for males and 59.3 years for females, patients were divided into three groups:

Control Group (n = 4) ; Received no prophylactic hydration.

Postoperative Hydration Group (n = 6) Received intravenous fluids after the onset of hypotony.

Preoperative Hydration Group (n = 40) : Received prophylactic intravenous hydration.

Intraocular pressure (IOP) was monitored at various intervals pre- and postoperatively.

Results: The mean IOP was 18 ± 2 before surgery. Patients were treated medically with diuretics. The experimental group, which received serum therapy before surgery, exhibited a higher mean IOP initially but did not experience any cases of choroidal detachment.

Since the p-value (0.0345) is less than the significance level ((alpha = 0.05)) , we reject the null hypothesis.

This means there is a statistically significant difference between the mean intraocular pressures of the control group and the experimental group.

Conclusion: The incidence of choroidal detachment and the degree of IOP reduction were compared between groups. Our findings suggest that prophylactic intravenous hydration is a safe and effective strategy for minimizing the risk of choroidal detachment and postoperative hypotony following trabeculectomy.