Donepezil-Associated Bradycardia in An Elderly Patient with Dementia: A Case Report

Authors

  • Dr. Jyothi Patri MD, MHA, DipABLM, DABFM, FAAFP, HMDC Associate Director and Senior Faculty, Heritage Valley Family Medicine Residency Program, Beaver Falls, PA, USA Author
  • Dr. Shravan Gangula MD, FAAFP Coffeyville Regional Medical Center, USA Author

DOI:

https://doi.org/10.47363/bjz2fj84

Keywords:

Donepezil, Bradycardia, Elderly, Dementia

Abstract

Acetylcholinesterase inhibitors are commonly prescribed for the management of Alzheimer’s disease and other dementias [1]. While generally well tolerated, these agents may cause serious cardiovascular adverse effects, particularly in frail older adults [2]. We report a case of symptomatic bradycardia and hypotension in an 85-year-old patient with dementia associated with donepezil use, which resolved after discontinuation of the medication [3].

Author Biographies

  • Dr. Jyothi Patri MD, MHA, DipABLM, DABFM, FAAFP, HMDC, Associate Director and Senior Faculty, Heritage Valley Family Medicine Residency Program, Beaver Falls, PA, USA

    Associate Director and Senior Faculty, Heritage Valley Family Medicine Residency Program, Beaver Falls, PA, USA

  • Dr. Shravan Gangula MD, FAAFP, Coffeyville Regional Medical Center, USA

    Coffeyville Regional Medical Center, USA

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Published

2026-01-22