Essential Oils as A Potential Neuroprotective Remedy for Alzheimer’s Disease

Abstract

Alzheimer’s disease is a complex neurodegenerative disorder characterised by cognitive decline and progressive memory deterioration. Multiple hypotheses have been proposed to elucidate the pathophysiology of the phenomenon in question. At present, there exists a limited number of pharmaceutical interventions for the management of Alzheimer’s disease, with the treatment options primarily focused on alleviating symptoms rather than addressing the underlying causes of the condition. The objective of this study is to conduct a comprehensive review of the pertinent in vitro, in vivo, and clinical research pertaining to the potential therapeutic applications of essential oils in the management of Alzheimer’s disease. Data was collected by conducting a search in scientific databases, including google scholar, Scopus, ScienceDirect and PubMed. A comprehensive investigation was undertaken to explore the utilisation of diverse essential oils in various models of Alzheimer’s disease. The findings of our literary investigation indicate promising outcomes concerning the diverse essential oils that have been examined in research on Alzheimer’s disease. These oils have demonstrated notable effects in regulating the disease’s pathology through their anti-amyloid, antioxidant, anticholinesterase, and memory-enhancement properties.