Journal of Neurology Research Reviews & Reports
Journal of Neurology Research Reviews & Reports is an open access peer-reviewed journal from the publishers of Scientific Research and Community (SRC) which publishes articles in the form of written, video and power-point presentations from the arena of Neurology Research Reviews. The journal focuses to build up accessing the complete content of articles freely from online for reader’s perusal. Article acceptance will be in the form of research, review, case reports, analysis, magazines, editorials, opinion, communications, mini-review, short communications, picturized, book review, video type and power point presentations (PPTS). Articles can be submitted through online from https://srcpublishers.com/neurology-jnrrr/user/register or can send through an e-mail with attachment for neurosciences@onlinescientificresearch.info 1.57 Impact Factor 84.5% Citations 90% Acceptance
Teaching Video Games as a Leisure Skill to Arab American Children with Autism Spectrum Disorder Using Video Modeling: A Multiple Baseline Study
Children with autism spectrum disorder (ASD) frequently experience difficulties engaging in leisure activities because of deficits in social communication and interaction. Participation in meaningful leisure activities contributes to improved quality of life, emotional well-being, and social engagement. Despite the importance of leisure skills, limited research has examined interventions designed to teach leisure activities to culturally diverse populations. The purpose of this study was to investigate the effectiveness of video modeling in teaching an active video game as a leisure skill to Arab American children with ASD. Three elementary-aged Arab American children diagnosed with ASD participated in the study. A multiple baseline design across participants was employed to evaluate the effects of video modeling on acquisition of the Nintendo Switch game Just Dance. Results demonstrated a functional relation between video modeling and increased independent performance for all participants. Participants maintained the acquired skills after withdrawal of the intervention. Students and teachers reported positive perceptions regarding the intervention. Findings support video modeling as an effective and socially valid intervention for promoting leisure skills among Arab American children with ASD.
Copyright (c) 2026 Journal of Neurology Research Reviews & Reports
Ultra Weak Photon Environments as a Potential Adjunctive Approach for Phantom Limb Pain: A Neuroplasticity Based Hypothesis Review
Phantom limb pain (PLP) is a debilitating neuropathic pain syndrome affecting most amputees and remains difficult to treat effectively. Current therapeutic approaches, including medications, mirror therapy, neuromodulation, and virtual reality, often provide incomplete or inconsistent relief. Mirror therapy has demonstrated significant efficacy in unilateral amputees; however, it is fundamentally limited in patients with bilateral limb loss because it requires at least one intact contralateral limb for visual feedback generation. There is a need to identify bilateral amputees as a major therapeutic gap and to explore non-visual, whole-body therapeutic frameworks for future investigation. Ultra-Weak Photon Environments (UWPEs) represent a novel non-contact environmental approach that may support nervous-system regulation, cortical reorganization, autonomic balance, and recovery sleep. This review proposes that UWPE may reduce PLP through mechanisms involving neuroplastic modulation, sensory-motor stabilization, and biological coherence. A speculative neurobiological information-processing framework is further discussed in which persistent pathological “information mismatch” between the brain and the missing limb contributes to phantom pain generation. Although the proposed mechanism remains hypothetical, findings from neuroscience, mirror therapy studies, biophoton research, and photo biomodulation literature provide rationale for future investigation. Controlled clinical studies are warranted.
Real-World Quality of Life Observations in Individuals with Lupus Using Ultra-Weak Photon Environment Products: A Descriptive Case Series
Systemic lupus erythematosus (SLE) and related autoimmune disorders are chronic inflammatory diseases associated with fatigue, pain, sleep disturbance, mood changes, and reduced quality of life. Despite advances in medical management, many patients continue to experience persistent symptoms and seek complementary wellness approaches. This report summarizes a series of unsolicited real-world user feedback cases describing quality-of-life improvements following use of Tesla BioHealing® products designed to create an Ultra-Weak Photon Environment (UWPE). Reported benefits included reduced fatigue, improved sleep quality, decreased pain, enhanced mood, reduced headaches, and increased daily functioning. These observations are anecdotal and do not establish causation, but they may support future observational and controlled studies evaluating wellness-oriented environmental interventions in individuals living with lupus and related autoimmune conditions.
Recovery Sleep in an Ultraweak Photon Environment: A Unified Neurorestorative Paradigm Across Neurodegenerative and Neurovascular Disorders
Background: Neurodegenerative and neurovascular disorders, including Parkinson’s disease, Alzheimer’s disease, chronic stroke, traumatic brain injury, and Amyotrophic Lateral Sclerosis, remain major unmet clinical challenges worldwide. Despite distinct clinical presentations, these disorders share overlapping biological mechanisms, including mitochondrial dysfunction, oxidative stress, neuroinflammation, impaired neurovascular regulation, disrupted neural signaling, sleep disturbance, and reduced cellular resilience. Ultraweak Photon Emission (UPE) has emerged as a measurable biological phenomenon associated with mitochondrial-redox metabolism, neural activity, cerebral blood flow, glutamate signaling, electroencephalographic activity, and neurodegenerative processes. Objective: To review current evidence regarding UPE and Ultra-Weak Photon Environments (UWPEs) as potential biomarkers and investigational neurorestorative approaches for neurological disorders. Methods: A narrative review was conducted of published experimental, preclinical, and early clinical studies involving UPE, biophotonic signaling, neural stem cells, human brain photon monitoring, and recovery sleep within UWPEs generated by ultraweak biophoton emitters. Results: Published evidence demonstrates that living brain tissue emits detectable UPE signals that can be differentiated from background photon noise. UPE has been associated with mitochondrial respiration, reactive oxygen species generation, lipid peroxidation, acetylcholinesterase activity, hippocampal memory impairment, neural stem cell differentiation, and task-related human brain activity. In three randomized controlled trials, recovery sleep within a UWPE generated by ultraweak biophoton emitters was associated with improvements in multiple neurological and functional domains, including enhanced brain activity, improved qEEG-based functional brain measures, reduced brain functional age, improved sleep quality, increased energy, improved motor function, enhanced cognition and emotional well-being, better daily functioning, and improved quality of life. These findings suggest that prolonged nighttime exposure to a UWPE may support neurofunctional recovery through modulation of mitochondrial-redox biology, sleep-mediated restoration, neurovascular regulation, and neural-network function. Conclusion: Current evidence supports UPE as a biologically meaningful optical marker of brain physiology and redox-metabolic state. Recovery sleep within an Ultra-Weak Photon Environment represents a plausible investigational neurorestorative paradigm that warrants further mechanistic investigation and large-scale controlled clinical studies.
Navigating Renal Vascular Anomalies: A Case of Unilateral Arterial and Venous Duplication
Blood supply of kidney is significant due to its integral function of excretion and osmoregulation. Each kidney supplied by single renal artery, lateral branch from the abdominal aorta and drained by single renal vein draining into IVC. Present case describes clinically significant variation of kidney with unilateral duplication of renal vessels. In this case, right kidney is supplied by the two renal arteries arising from the aorta and drained by two renal veins. The accessory renal artery here traversed between two renal veins. This can compromise the blood supply due to impingement. Duplication of renal vessels holds significance in renal surgeries as it will take longer time of anastomosis and can create technical difficulties during mobilization. Kidneys are most commonly transplanted organs, so knowledge of such variations which can affect the success of transplantation is significant. 20-25% of the cardiac output is received by kidneys so variations in the renal vessels affecting circulation may lead to clinical manifestations related to cardiovascular system too. Urologists, radiologists, and vascular surgeons need to know about these variations for segmental resections, renal transplantations, treatment of abdominal aorta aneurysms, renal stenosis treatment and clinical evaluation of renal vascular hypertension.
A Possible Treatment for Memory Loss and Associated Disorders
About two years or so ago I began to have memory difficulties, sporadic nominal aphasia. I would have to search for names of things and particularly of people. They just would not be there when I wanted them but often would appear about five minutes later. As a forerunner of Alzheimer’s disease, it was particularly concerning. Recently, however, looking through the literature I found Butterfly Pea Flower tea mentioned as a possible treatment.
From T-Patterns to T-Strings to T-Societies
By the mid-1940s, two world wars in less than 40 years saw many millions killed by what were considered some of the world’s most advanced societies. Researchers wanted to make sense of such a world. Some looked to biology and primatology in their pursuit to better understand human behaviour. In 1967, Desmond Morris published The Naked Ape, detailing his primatological perspective of the social behaviour of humans, and in 1965, Niko Tinbergen’s book Animal Behavior became an influence for many researchers in the field. The 1973 Nobel Prize in Physiology or Medicine was shared by Tinbergen, Konrad Lorenz, and Karl von Frisch for their ethological discoveries regarding social behaviour patterns in animals.
Copyright (c) 2025 Journal of Neurology Research Reviews & Reports
Treatment of Chronic Muscle Spasm and Pain with the CMECD® Procedure
It has been noted by multiple researchers that there is Spontaneous Electrical Activity (SEA) at painful trigger points. This author has studied chronic muscle spasm and found that SEA is always present and appears to be the cause for the chronic nature of muscle spasm and resulting chronic pain. Chronic muscle spasm and resulting chronic pain can last for years and cases where the spasm lasted for decades were not only found but successfully treated with the CMECD® procedure. This procedure consists of EMG guidance searching for the SEA and using a combination of phenoxybenzamine, Lidocaine and dexamethasone to extinguish the SEA. Large areas of muscle often need to be treated. Thanks to lidocaine acting as an antiarrhythmic, the SEA is extinguished within seconds and the phenoxybenzamine then takes over after about one hour. With the resolution of the SEA, the muscle can immediately relax. The phenoxybenzamine forms a covalent bond on the alpha motoneuron receptor and the result is a duration of action of 2-3 months. This is enough time for the muscle to recover the prolonged effect of ischemia resulting from the prolonged spasm. Muscles treated in this fashion need only a single injection. Recurrences are rare and only occur if there is a repeat overuse or traumatic injury. The CMECD® procedure is available for use by any medical caregiver that is licensed to give injections. The ability to permanently relieve chronic pain without the use of opioid drugs should prompt interest in this procedure.
Autism & Mental Health – How Different Individuals are Impacted
Statement of the Problem: Women who suffer mental health issues, because of Autism Spectrum Disorder has a significant impact on their lives, especially if they’ve suffered trauma because of the bullying/discrimination/cruel remarks & actions from other people. Autism can impact one’s mental health in many ways (childlike behavior), social anxieties or overload. The impact of mental health can also be experienced when the person does not have a good quality of life for themselves (eg employment, independent living skills), or have support from family/friends/society). I will be discussing how my mental health was impacted, by living not only in a black hole, in the early days, but how I’ve also put strategies in place in becoming a strong, determined and very resilient woman because of my mental health being pushed down by others. I’ll also be discussing some trauma experiences that I’ve had in my life, which has caused me significant pain & suffering but has shaped me the way I am now today!
Geometric Unified Learning for Neurological Disease Detection
This talk introduces Geometric Unified Learning (GUL), a cutting-edge technology designed to enhance the detection of neurological diseases and brain disorders. By leveraging reusable building blocks and techniques rooted in differential geometry, GUL addresses critical challenges in deep learning, including data overfitting, inefficiencies, and lack of interpretability. It provides clinicians with transparent, trustworthy, and highly interpretable predictions by identifying intrinsic patterns within complex brain structures. GUL’s efficient data processing and simultaneous search and learning capabilities enable robust, flexible, and resource-efficient solutions. By reducing the time and effort required for data analysis, GUL not only supports better clinical decision-making but also saves valuable time for healthcare providers, ultimately improving patient outcomes. This approach tackles challenges like data quality, scalability, and parameter tuning, offering a powerful alternative to traditional deep learning models.
Child Development Leading to The Pursuit of Virtues and The Avoidance of Vices
Optimizing the social, emotional, moral and cognitive development of children will support prosocial behaviour and peaceful societies. To accomplish these goals, efforts need to start from birth with authoritative parenting to achieve secure attuned attachment between caregiver and child. Such parenting should eliminate the toxic stress associated with the authoritarian approach and the lack of direction seen with permissive or uninvolved parenting. Early literacy is the key to building character using the vehicles of modelled behaviours, reading stories with a moral and that teach a lesson and Human Relations Programs for Children. Benevolent mindfulness characterized by emotional empathy, compassion and helping behaviours will result from proper parenting and successful character education. The resultant ability to think in a complex fashion where virtues are pursued and vices avoided should facilitate resistance to false narratives and non-violent conflict resolution. Avoiding Adverse Child Experiences has been shown to minimize depression, violence perpetration and other problem behaviours and disorders. When there are educational and professional resources in play to support the development of children in communities, a responsible, caring citizenry can be anticipated.
Neurophysiological Grading Tool of Ulnar Nerve Entrapment Across Wrist and Across Elbow with Case Presentation
Ulnar nerve entrapment across the elbow (UNEAE) and across wrist (UNEAW) is the second most common entrapment of the hand after carpal tunnel syndrome. There are few gradings available for UNEAE and lesser in UNEAW. The aim of this research is; To create a clinically appropriate ulnar nerve entrapment grading tool to covers both area of entrapment in one research paper. To see the relation of sensory nerve involvement across wrist with the entrapment across elbow and to evaluate its effectiveness in terms of compatibility with previous research, without any invasive tests like needle EMG examination. To identify the lesion below and across wrist in terms of to support the clinical Physiologist (CP) to grade them properly and also help the consultant in deciding to treat with conservative or surgical treatment. To compare the recording from the first dorsal interosseous (FDI) muscles with the abductor digiti minimi (ADM) muscle to see which muscle is more sensitive and shows early changes in ulnar nerve entrapment. The proposed revised grading system is based on more nuanced, descriptive categories, ranging from “normal”, “early”, “mild”, “moderate” and “severe”. To create full grading system of UNEAW and UNEAE some additional category of clinical grading is therefore proposed.
Observational Case Series of Three Individuals with Amyotrophic Lateral Sclerosis Using Biophoton Generators
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by degeneration of upper and lower motor neurons, leading to progressive weakness, bulbar dysfunction, and respiratory failure. Current therapeutic options provide limited benefit, and management remains largely supportive. Observational case reports may contribute to hypothesis generation in conditions with significant unmet clinical need. Objective: To document and descriptively analyze patient- and caregiver-reported observations temporally associated with proximity use of wellness devices in individuals diagnosed with ALS. Methods: We report a three-case observational series derived from patient and caregiver correspondence. In each case, individuals diagnosed with ALS used Tesla BioHealing® BioHealers intended for general wellness, near the body. Use occurred outside of formal clinical protocols. No standardized neurological scales (e.g., ALSFRS-R), quantitative motor testing, electrophysiological monitoring, or blind assessments were performed. Outcomes were based exclusively on self-report. Results: Across cases, reported domains included perceived improvements in peripheral circulation, hand mobility, swallowing coordination, speech clarity, bowel regularity, sleep quality, and energy levels. One case described a reported four-year period of clinical stability with preserved energy. Sensory changes (e.g., tingling, altered limb perception) were also described. No device-related adverse effects were reported. However, no objective clinical measurements were obtained to confirm functional change or disease stability. Conclusion: This three-case observational series documents patient-reported positive experiences associated with proximity use of wellness devices in individuals diagnosed with ALS. Due to the uncontrolled design, reliance on self-report, and absence of objective outcome measures, no conclusions regarding causality or clinical efficacy can be drawn. These observations are hypothesis-generating and support the rationale for prospective, controlled feasibility studies incorporating standardized neurological metrics and appropriate comparators.
The Bio-Dao Code: A Systems-Level Framework for Neurological Aging, Functional Decline and Recovery
Despite substantial advances in acute neurological care, the prevalence of chronic neurological disorders, age-associated functional decline, and long-term disability continues to rise. This discrepancy suggests not merely a therapeutic gap, but a conceptual limitation in prevailing neurological paradigms, which remain largely organ- and disease-centered. In this review, we introduce the Bio-Dao Code, a systems-level interpretive framework that conceptualizes neurological aging and chronic disease as state-dependent processes governed by repair capacity, systemic dissipation, and network-level coherence. Rather than proposing a therapeutic intervention, the Bio-Dao Code integrates insights from electrophysiology, network neuroscience, and sleep biology to provide a unifying structure for interpreting long-term neurological trajectories. We outline a four-layer life-system model, describe five governing principles relevant to neurological sustainability, and discuss implications for research design, longitudinal biomarkers, and ethical decision-making in neurology. This framework is intended to support hypothesis generation and scholarly dialogue rather than clinical prescription.
Psychiatric Side Effects Caused by Tirzepatide
The work reveals the issue of neuropsychiatric (psychological) safety of GLP-1 receptor agonists of tirzapatide used for the treatment of type 2 diabetes mellitus, obesity and eating disorders. The complex advantages of tirzepatide in relation to metabolic and psychological health are highlighted, making it a safe and effective remedy for patients with severe obesity (BMI>30), including night eating syndrome. The profile of psychiatric side effects when taking tirzepatide is described. The emphasis is placed on the fact that a number of patients use these drugs as a form of corrective (cleansing) behavior. In this regard, when prescribing these drugs, comorbid mental disorders in the patient and early maladaptive patterns should be taken into account.
Impact of Biophoton Treatment on Functional Brain Age in Patients with Parkinson’s Disease Based on EEG-Derived Metrics
Background: Parkinson’s disease (PD) is associated with progressive neurophysiological decline that is incompletely captured by chronological age or clinical scales alone. Functional brain age derived from electroencephalography (EEG) provides a quantitative marker of neural aging and functional integrity. Objective: To evaluate the effect of biophoton-based treatment on EEG-derived functional brain age in patients with Parkinson’s disease compared with untreated controls. Methods: Functional brain age was estimated by EEG metrics at baseline and last follow up in 16 participants (10 treatment, 6 control). The primary outcome was change in functional age. Between-group comparisons were performed using Welch’s t-test, and an analysis of covariance (ANCOVA) was conducted adjusting for baseline functional age. Results: Treated patients demonstrated a significant reduction in functional brain age (mean 5.1 years) at the last follow up, whereas controls showed no change. After adjustment for baseline functional age, the treatment effect remained significant, with a large effect size. Conclusion: Biophoton treatment was associated with a clinically meaningful and statistically significant improvement in EEG-derived functional brain age in patients with Parkinson’s disease (P<0.01). These findings support further investigation of biophoton-based interventions as a potential neurofunctional modulator in neurodegenerative disease.
The Relationship Between ADHD and Addictive Behaviours: Implications for Economic and Health Outcomes
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder that often continues into adulthood, resulting in corresponding adverse social, occupational, and economic costs. Addictive behaviours, substance use disorders (SUDs), or behavioural addictions are some of the most serious comorbidities with ADHD. This narrative review explores how ADHD is interconnected with addictive behaviours, focusing on prevalence, underlying psychological/neurobiological factors, and overall implications with regard to healthcare and economic productivity. Data from available scientific evidence suggests that this phenomenon is grounded in a bidirectional relationship wherein core symptoms of ADHD, especially impulsivity and regulatory dysfunction, create higher vulnerability to addictive behaviours, but concurrent addictive behaviour exacerbates functional deficits in ADHD.
Attention-Deficit/Hyperactivity Disorder
Functional and Structural Recovery in Myasthenia Gravis and Rheumatoid Arthritis Using a Biophoton-Emitting Device: A Case Report
Background: Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating skeletal muscle weakness due to impaired neuromuscular transmission, most often mediated by antibodies against the acetylcholine receptor (AChR). Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that leads to persistent synovial inflammation, joint deformity, and systemic complications. Standard management for both disorders frequently require long-term immunosuppressive therapy, yet many patients experience incomplete responses or adverse effects. Novel, non-invasive therapeutic strategies are therefore needed. Biophoton therapy, which leverages ultraweak photon emissions to influence cellular metabolism, oxidative stress, and intercellular signaling, has shown promising preliminary results in a variety of chronic neurological and systemic conditions. Objective: To describe functional, structural, and systemic improvements in two patients with MG one with concomitant RA following the use of Tesla BioHealer devices, which emit biophotons in biologically relevant wavelength ranges. Methods: This case report documents photographic, functional, and subjective outcomes in two patients after consistent daily use of Tesla BioHealer devices. The first patient, a 64-year-old female with both MG and RA, used one device continuously for 56 days, later increasing to two. The second patient, a 70-year-old female with MG, used two devices daily for four weeks; her spouse, with chronic obstructive pulmonary disease (COPD)/emphysema, also underwent biophoton exposure. Results: In the first case, baseline photographs revealed pronounced swelling and deformity of the hands consistent with advanced RA and MG-related muscle weakness. After treatment, marked reductions in swelling and deformity were observed, alongside improved joint mobility, enhanced comfort, and greater systemic vitality. In the second case, the patient reported enhanced muscle strength, reduced fatigue, and improved quality of life, while her spouse reported better breathing and reduced reliance on nebulizer therapy. These changes were corroborated by family members and treating clinicians. Conclusion: These cases provide preliminary evidence that biophoton therapy may improve both structural and functional outcomes in complex autoimmune and neuromuscular conditions. Although limited by anecdotal design and lack of standardized clinical measures, the speed and magnitude of observed benefits support the need for controlled clinical trials to further assess the role of biophoton-generating devices in MG, RA, and related disorders.
Biophoton Therapy in Lyme Disease: Neurophysiological and Bioenergetic Improvements Over 4 Weeks - A Case Report
Background: Lyme disease frequently results in persistent neurological dysfunction even after standard antibiotic therapy, with symptoms including cognitive impairment, fatigue, and impaired vigilance. Biophoton therapy, a non-invasive intervention that emits ultra-weak photons, has been proposed to restore mitochondrial function, support systemic bioenergetics, and improve neural efficiency. Methods: We present a case study of a 54-year-old female patient with chronic Lyme disease who underwent continuous biophoton therapy for four weeks using two Tesla BioHealers. Neurophysiological outcomes were assessed at baseline, Week 2, and Week 4 using quantitative EEG (qEEG), event-related potentials (ERPs), and behavioral reaction times. Patient-reported outcomes (SF-36) and pulmonary function (spirometry) were also measured. Systemic energy balance was evaluated using Bio-Well gas discharge visualization technology to quantify organ-specific and integral energy changes. Results: The patient demonstrated progressive improvement in quality of life (SF-36: ~1,200 baseline to ~3,300 at Week 2) and pulmonary function (spirometry: ~150 baseline to ~430 at Week 2). EEG findings showed early normalization of posterior alpha activity, reduced theta/beta ratio, and sustained improvement in reaction time (470 ms baseline to 411 ms a Week 4). ERP analysis revealed a transient improvement in visual processing latency at Week 2. Bio-Well assessments indicated a systemic shift from fragmented and depleted energy at baseline to coherent, balanced energy fields by Week 4. All organs with baseline energy below 4 Joules (×10-²) increased above this threshold, with a mean overall energy gain of +0.73 per organ. Conclusion: Biophoton therapy was associated with multidimensional improvements in cortical efficiency, systemic energy balance, and functional outcomes in a patient with chronic Lyme disease. These findings highlight the potential of biophoton therapy as a novel non-invasive intervention for post-infectious neurological dysfunctions, warranting further validation in controlled clinical studies.
Biophoton Therapy for Chronic Pain: Clinical and Real-World Breakthrough
Background: Chronic pain presents a major clinical and public health challenge, particularly among patients with neurological and inflammatory diseases. Current pharmacological treatments often carry risks of side effects or dependency, highlighting the urgent need for safe, effective, non-invasive alternatives. Objective: To evaluate the safety and efficacy of Tesla BioHealing® Biophoton Generators in reducing chronic pain, based on data from clinical trials and real-world users. Methods: A total of 194 patients diagnosed with chronic conditions, including Parkinson’s disease, chronic stroke, traumatic brain injury, post-COVID syndrome, Alzheimer’s disease, and Lyme disease, participated in seven clinical trials conducted from 2020 to 2025. Pain levels were assessed using the SF-36 survey before and after 4 weeks of biophoton exposure. Additionally, real-world outcomes from over 45,000 users were analyzed via post-marketing surveys and testimonials. Ancillary studies included infrared thermography, meridian energy mapping, and dark-field microscopy of live blood samples. Results: No adverse events were reported. Among 87 participants with moderate to severe baseline pain, only 21 remained symptomatic after 4 weeks, a 76% reduction. A randomized, triple-blinded, placebo-controlled trial on arthritis confirmed statistically significant pain relief in the biophoton group (p<0.01). Real-world users with severe pain reported average pain score reductions from 9.52 to 5.26. Infrared imaging showed reduced inflammation, meridian analysis revealed increased bioenergy circulation, and live blood microscopy confirmed restored fluidity and reduced oxidative stress. Conclusion: Tesla BioHealing® Biophoton Generators provide a novel, drug-free therapy for chronic pain with strong safety and efficacy signals across diverse conditions. This technology offers a promising alternative to opioid-based therapies and supports broader applications in integrative neurology and pain medicine.
Non-Invasive Biophoton Therapy Restores Visual Function in Advanced Glaucoma: A Human and Canine Case Report
Background: Glaucoma is a leading cause of irreversible blindness worldwide, characterized by progressive retinal ganglion cell loss and optic nerve degeneration. Current therapies focus on lowering intraocular pressure but do not reverse established visual deficits. Novel, non-invasive approaches aimed at neuroregeneration are urgently needed. Objective: To explore the potential of biophoton therapy a non-pharmacologic intervention delivering light in the 500-1000 nm range to restore visual function in cases of advanced glaucoma. Methods: Two real-world case observations were documented: a human patient with a history of five glaucoma surgeries and 50% vision loss in one eye, and a canine diagnosed with secondary glaucoma and complete functional blindness. Both subjects received biophoton therapy via a non-heating biophoton-emitting eye mask (human) or stationary biophoton generators placed near the sleeping area (canine). No additional pharmacologic or surgical interventions were introduced during the observation period. Results: Within four weeks of nightly biophoton eye mask use, the human subject reported complete resolution of visual fog and restoration of color perception and brightness in the affected eye. The canine subject demonstrated regained visual tracking and environmental navigation within two weeks of therapy, despite an initial prognosis of irreversible blindness. In both cases, the improvements occurred in the absence of medication changes or additional treatments. Conclusion: These findings suggest that biophoton therapy may stimulate visual recovery in cases of advanced glaucoma, potentially through mechanisms involving mitochondrial activation, neuroprotection, and improved microcirculation. While anecdotal, the observed cross-species visual restoration supports the biological plausibility of biophoton-mediated optic nerve regeneration. Controlled clinical studies are warranted to systematically evaluate efficacy, dose-response, and mechanisms of action.
Non-Invasive Biophoton Therapy for Neurocognitive and Physical Recovery in Retired Athletes with Traumatic Brain Injury: A Pilot Study in Former NFL Players
Objective: This pilot observational study evaluated the impact of nightly exposure to biophoton energy therapy delivered via Tesla BioHealer devices on cognitive function, physical vitality, and emotional well-being in retired NFL players experiencing chronic symptoms of traumatic brain injury (TBI). Methods: Twelve retired NFL athletes with persistent neurocognitive, physical, and emotional impairments related to TBI used Tesla BioHealers overnight (≥8 hours/night) for an initial 60-day period, with an optional extension to 120 days. Weekly interviews and bi-weekly surveys assessed changes in sleep quality, memory, pain, energy levels, emotional stability, and interpersonal relationships. Additionally, one participant underwent a blinded, placebocontrolled EEG study with serial assessments to measure physiological changes over six weeks. Results: By the first night, 100% of participants experienced uninterrupted sleep. By day 30, 85% reported improved cognition and reduced pain. By day 60, all participants demonstrated full mental clarity, enhanced physical and emotional functioning, and restored sexual performance. These effects persisted through the extended follow-up. Quantitative EEG from the controlled case revealed improvements in frontal alpha asymmetry, posterior peak frequency, and attentional markers, correlating with enhanced mood, cognitive readiness, and neuroregulation. One participant’s SF-36 score improved by 42% after four weeks of active treatment. Conclusion: Biophoton therapy may offer a non-invasive, restorative approach for improving sleep, neurocognitive performance, and quality of life in individuals with chronic TBI. These preliminary results underscore the need for larger, randomized clinical trials to validate therapeutic efficacy and explore underlying mechanisms.
Biophoton Therapy Restores Hemorheology in Chronic Stroke: Live Blood Evidence of Microvascular Recovery
Background: Chronic stroke is associated with long-term impairments in microvascular circulation, blood rheology, and cellular metabolism, which collectively limit recovery. Biophoton generators emit ultraweak, coherent photons that may restore mitochondrial function, enhance red blood cell morphology, and improve systemic perfusion. Methods: A 70-year-old male with chronic ischemic stroke underwent 24 days of continuous exposure to Tesla BioHealer® devices. Capillary blood samples were collected on Days 0, 2, 14, 17, and 24 and analyzed using darkfield live blood microscopy. Five hematologic parameters RBC aggregation, fibrin thread density, membrane integrity, plasma debris, and immune or platelet activity were semi-quantitatively scored (0–4), yielding a raw severity score (0–20) and a composite blood health score (0–10). Results: At baseline, the patient exhibited severe rouleaux formation, dense fibrin networks, and distorted erythrocyte morphology (composite score = 2.0). By Day 24, >80% of RBCs were freely separated with clear plasma and no detectable fibrin, yielding a composite score of 9.5 and a >90% reduction in the raw severity score. These findings suggest significantly improved blood fluidity, oxygen delivery capacity, and microvascular integrity. Conclusions: Biophoton therapy produced rapid, sustained improvements in blood morphology and rheology in a chronic stroke patient. These hematologic changes may reflect systemic recovery mechanisms observed in larger clinical studies, including improved cerebral perfusion and neurofunctional restoration. Controlled trials are warranted to further evaluate biophoton therapy as a noninvasive adjunct for stroke rehabilitation.
Biophoton Therapy Reverses Electrophysiological Deficits in Chronic Traumatic Brain Injury: Quantitative EEG Evidence of Cognitive and Network Recovery
Background: Chronic traumatic brain injury (TBI) is a debilitating condition lacking effective restorative treatments. Patients often experience persistent cognitive, emotional, and neurological impairments due to unresolved network-level dysfunction. Current therapeutic options provide limited recovery, underscoring the urgent need for novel neuromodulation strategies. Objective: This study investigates the use of biophoton therapy a non-invasive, quantum-based light energy modality—as a novel intervention to improve brain function in chronic TBI patients using quantitative EEG (qEEG) and event-related potential (ERP) biomarkers. Methods: Four patients with chronic TBI underwent resting-state EEG and ERP assessments at baseline, 2 weeks (placebo or early exposure), and 4 to 6 weeks following daily exposure to strong biophoton generators. EEG data were analyzed for changes in posterior alpha peak frequency, frontal theta/beta ratio, frontal alpha asymmetry, EC/EO alpha ratio, and Brodmann area Z-scores. ERP tasks evaluated visual/auditory processing and working memory. Results: Placebo exposure produced no measurable change in cognitive or neural function. In contrast, biophoton therapy resulted in consistent electrophysiological improvements across patients, including: (1) Increased posterior alpha frequency (e.g., 9.4 → 10.4 Hz). (2) Reduced theta/beta ratios (e.g., 0.97 → 0.75), indicating improved attention. (3) Enhanced EC/EO alpha ratios, suggesting greater arousal regulation. (4) Decreased ERP latencies (e.g., N4 reduced by 48 ms), indicating faster working memory. (5) Normalization of Brodmann area z-scores in sensorimotor, frontal, and temporal regions. Conclusion: Biophoton therapy represents a promising, drug-free intervention for restoring neurophysiological function in chronic TBI. This novel modality improves both cognitive performance and underlying brain network activity, as demonstrated by objective EEG biomarkers. These findings warrant further clinical investigation to establish biophoton therapy as a viable treatment pathway for unmet neurorehabilitation needs in TBI.
Quantitative EEG Reveals Cognitive and Motor Restoration After Biophoton Treatment in Chronic Stroke
Background: Chronic stroke is a leading cause of long-term neurological disability, with limited therapeutic options for restoring brain function beyond the acute recovery window. Recent advances in biophoton therapy suggest a novel approach to promote neuroplasticity through non-invasive, energybased mechanisms. This study aimed to evaluate the neurophysiological effects of strong biophoton generator therapy in patients with chronic stroke using quantitative EEG (qEEG) and behavioral metrics. Methods: Five patients aged 63-77 years with confirmed chronic stroke received nightly exposure to four strong biophoton generators for 4 consecutive weeks. EEG recordings were acquired at baseline, Week 2, and Week 4 using the BrainView system. Primary outcomes included posterior alpha frequency, theta/beta ratio, frontal alpha asymmetry, and event-related potentials (P2, P3, P3b). Secondary outcomes included reaction time, error rate, and patient reported symptoms. EEG data were analyzed longitudinally to assess progressive neurofunctional change. Results: Across patients, biophoton therapy was associated with increased posterior alpha frequency (mean +0.3–0.5 Hz), reduced theta/beta ratios (mean –0.05 to –0.1), and shortened P3 and P3b latencies (mean –16 to –20 ms), indicating enhanced cortical processing and attentional regulation. Behavioral improvements included reduced reaction time variability, fewer missed responses, and self-reported improvements in balance and strength. Placebo-treated control data showed no significant EEG or behavioral change. Conclusion: Biophoton therapy may stimulate measurable recovery in chronic stroke patients, as reflected by improved EEG biomarkers and cognitive behavioral outcomes. These findings highlight the potential of bioenergetic interventions to activate latent neural plasticity, offering a promising nonpharmacological option for post-stroke rehabilitation.
Enhancing Blood Fluidity and Physiological Markers in Early Stage Alzheimer’s Disease Using Biophoton Generators: A Case Study
Background: Impaired blood fluidity and microcirculation are increasingly recognized as contributors to the pathophysiology of Alzheimer’s disease (AD). This study investigates the effect of strong biophoton generators on blood quality, oxygenation, and cellular morphology in a patient with early-stage AD. Methods: A 59-year-old female with clinically diagnosed early-stage AD was exposed to four biophoton generators emitting coherent biophysical fields for ≥8 hours/day over 4 weeks. Blood samples were analyzed under a dark-field microscope at Baseline, Day 3, Day 5, Day 13, Day 18, and Day 27. Physiological markers assessed included blood viscosity, oxygen saturation, lipid profile, and cellular morphology. Results: By Day 3, blood became cleaner with reduced cell aggregation and increased oxygenation. By Day 5, further improvements in morphology and immune activation were observed. Day 13 and Day 18, showed reduced systemic pain and better sleep initiation without hormonal support. By Day 27, the patient displayed stabilized cell morphology, improved metabolism, and reduced dependence on medications. Conclusion: Biophoton therapy demonstrated a measurable improvement in blood fluidity, oxygen delivery, and systemic homeostasis. These changes may support neurological stabilization and pain reduction, offering a novel adjunctive approach for early-stage Alzheimer’s disease. Further controlled studies are warranted.
Quantitative EEG Evidence of Cognitive Restoration in Alzheimer’s Disease Following Biophoton Generator Therapy
Background: Alzheimer’s disease (AD) is marked by progressive cognitive and electrophysiological decline. Existing treatments offer limited symptomatic relief without reversing underlying pathology. Recent advances in biophoton therapy offer a novel, non-invasive strategy targeting mitochondrial and neural function. Objective: To evaluate the neurophysiological and cognitive effects of biophoton generator therapy in AD patients using quantitative EEG (qEEG) metrics. Methods: A randomized, triple-blinded, placebo-controlled clinical trial was conducted in 24 AD patients but 4 with serial EEG recordings were analyzed and reported in this article. Participants received nightly exposure to four strong biophoton generators for 2 to 4 weeks. Key EEG biomarkers assessed included posterior peak alpha frequency, theta/beta ratio, frontal alpha asymmetry, and P300 event-related potentials. Results: Placebo-phase data showed negligible EEG changes. In contrast, 2 to 4 weeks of active treatment led to increased alpha and beta power, reduced delta/theta activity, improved interhemispheric coherence, elevated EEG entropy, and enhanced P300 amplitude with shorter latency. Improvements were consistent across spectral, topographic, and ERP domains, suggesting cognitive restoration and neural plasticity. Conclusion: Strong biophoton generator therapy significantly improved qEEG biomarkers in AD patients within a short treatment window. These findings support further investigation into biophoton therapy as a safe, scalable intervention for neurodegenerative disorders.
Quantitative EEG Evidence of Functional Brain Recovery in Parkinson’s Disease Following Biophoton Therapy
Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with limited treatment options that address both motor and non-motor symptoms. Biophoton therapy, a non-invasive modality emitting biologically coherent light, may offer a novel approach to restoring functional brain activity in PD patients by promoting cellular repair and neurophysiological rebalancing. Methods: This study employed quantitative electroencephalography (qEEG) and event-related potential (ERP) biomarkers to assess the neurophysiological effects of biophoton therapy in multiple PD patients over a 4-week period. Each patient received continuous exposure to four strong biophoton generators. EEG metrics analyzed included posterior alpha peak frequency, theta/beta ratio, ERP latencies (P300, N2, P2, N4), reaction times, error rates, and brain region Z-scores associated with memory, attention, and motor control. Results: Patients demonstrated measurable neurophysiological improvements after biophoton therapy compared to baseline and placebo periods. Key findings included reductions in posterior alpha frequency (indicative of decreased CNS hyperarousal), enhanced attention and vigilance (lowered theta/beta ratios), faster ERP latencies (e.g., P300 latency improved from 340 ms to 320 ms), and improved motor performance (reaction time decreased from 841 ms to 582 ms). Z-score analysis revealed normalization across Brodmann Areas 1–10, reflecting restored memory, impulse control, and emotional regulation. No significant improvements were observed during placebo conditions. Conclusion: Strong biophoton generators produced consistent and clinically meaningful neurophysiological enhancements in Parkinson’s disease patients within a 4-week window. This therapy may represent a safe, non-pharmacologic, and scalable intervention capable of reversing functional markers of neurodegeneration. These results warrant larger controlled studies to confirm efficacy and explore underlying mechanisms.
Challenges in Diagnosis and Treatment of Cardioembolic Stroke in Young Adults
Cardioembolic ischemic stroke in young adults is an increasingly recognized clinical and public health challenge, differing in etiology and management from strokes in older populations. This retrospective study, conducted at the University Hospital of Annaba between 2020 and 2023, analyzed 48 cases of young adults aged 26 to 55 years diagnosed with cardioembolic stroke (TOAST type II). The most common underlying cause was patent foramen ovale (PFO), found in 62.5% of patients, followed by rheumatic mitral valve disease, acute myocardial infarction, atrial fibrillation, and infective endocarditis. Clinical presentations were typically characterized by hemiparesis and carotid territory infarctions. Management strategies were tailored to each etiology: PFO closure with antiplatelet therapy, anticoagulation for atrial fibrillation and valvulopathies, and guideline-based treatment for myocardial infarction and endocarditis. The in-hospital mortality rate was low (4.2%), but complications such as post-stroke depression, hemorrhagic transformation, epilepsy, and recurrence were observed. The findings underscore the need for early diagnostic workup, etiological classification, and personalized treatment strategies to optimize outcomes and prevent recurrence in young adults with cardioembolic stroke.
Neuroimaging in Hemiplegic Migraine - Case Report and Literature Review
A 29-year-old man presented to the emergency department with sudden-onset aphasia and left-arm weakness. The patient’s initial appearance was that of a healthy, well-developed male. He had not had any fevers, chills, cough, or nausea.