Journal of Pediatrics Research Reviews & Reports
type: channel
description: Journal of Pediatrics Research Reviews & Reports is an open access peer-reviewed journal from the publishers of Scientific Research and Community (SRC) which publishes articles in the form of written, video and power-point presentations from the arena of Pediatrics Research Reviews. The journal focuses to build up accessing the complete content of articles freely from online for reader’s perusal. Article acceptance will be in the form of research, review, case reports, analysis, magazines, editorials, opinion, communications, mini-review, short communications, picturized, book review, video type and power point presentations (PPTS). Articles can be submitted through online from https://www.onlinescientificresearch.com/submit-online or can send through an e-mail with attachment for pediatricsresearch@onlinescientificresearch.info or editor.jprrr@onlinescientificresearch.net 1.5 Impact Factor 84.5% Citations 90% Acceptance
publisher: Scientific Research and Community
language: en
publication name: Journal of Pediatrics Research Reviews & Reports
issn: 2755-0281
items: Reconstruction of the Phrenoesophageal Ligament: An Alternative to Avoid Post-Fundoplication Paraesophageal Hernia in Children
items: From Adverse Childhood Experiences to Digital Trauma-Informed Care: Rethinking Prevention Infrastructure for Pediatric and Population Health
items: A Retrospective Analysis of Clinic Epidemiological Features and Treatment Outcomes of Renal Cell Carcinoma University
items: Clinical and Genetic Characterization of Late-Onset Pompe Disease in an Adolescent Carrying a Rare GAA Coding Mutation
items: Salvage Re-Irradiation after Complex Treatment in Childhood Leptomeningeal Metastatic Medulloblastoma-Clinical Case withLiterature Review
items: Pediatric Psychology: Understanding the Mind of a Growing Child
items: Long-Term Evaluation of Supracondylar Fractures of the Humerus (SHF) in Elbow Extension in Children at the Pediatric Surgery Department of the Aristide Le Dantec University Hospital Centerin Dakar
items: A Horseshoe Appendix Duplex in Pediatrics: Do Not Misdiagnosethis Anatomical Anomaly!
items: Interleukin-10 Gene Expression Predicts Response to Therapy in Childhood Acute Lymphoblastic Leukemia
items: Screening of Helicobacter Pylori in Symptomatic Libyan Children
items: Six Years Old Boy with Post Covid-19 Isolated Palatal Paralysis, A Rare Clinical Case
items: Insight into Down Syndrome and its Rehabilitation
items: Covariates of Maternal Health Care Utilization: Evidence from Agricultural Households in Rural Nigeria
items: Phenotypic Spectrum and Diagnostic Challenges in Non-21-Alfa-Hydroxylase Deficiency Congenital Adrenal Hyperplasia: A Case Series from a Tertiary care Centre
items: A Parasitic Twin Diagnosed Prenatally As a Sacrococcygeal Teratoma: A Case Report
items: Neurodevelopmental Outcome of High-Risk Neonates At 24 Months of Age, With Respect to General Movements of Prechetl at Term or Within 3 Months of Age
items: Immature Intracranial Teratoma in Childhood - A Rare Clinical Case from Our Practice
items: Assessing the Effectiveness of HIV Counseling and Testing Programs: A Retrospective Study at an Apex Regional STD Centre in North India
items: Metabolic Characteristics in Obese Children
items: Standardization of Viral Neutralization Assay Used in To the Determination of Neutralizing Antibodies in the Evaluation Studies of the Cuban Vaccines against COVID-19
items: Does Simultaneous Intensity Modulated Radiotherapy with Temozolomide Increase the Radiosensitivity of Childhood Diffuse Intrinsic Pontine Glioma (DIPG)?- a Clinical Case from our Practice
items: Association between Breast Feeding and Development of Atopy
items: Long-Term Drug Treatment of a Giant Liver Hydatid Cyst in a Child
items: Re-Feeding Syndrome as a Rare Sequelae Post Resolution of DKA
items: Shaping ASD Pathways: Early PT vs. Late Support for Neurodiversity
items: Therapies for Anterior Teeth Affected by MIH in Children and Adolescents: Two Case Reports
items: Prevalence of Health Issues in Durres Children: Refractive Errors,Caries, and Scoliosis
items: Newborn COVID 19 Carriers: Experience from the Marrakech Neonatal Reanimation Department
items: Chemotherapy-Induced Febrile Neutropenia Managed on an Outpatient Basis at the Pediatric Hematology and Oncology Department of the Ibn Sina Children’s Hospital in Rabat
items: Proximal Hamstring Avulsion through Growth Plate: Case Reportof an Innovative Solution with Early Return to Sports

Reconstruction of the Phrenoesophageal Ligament: An Alternative to Avoid Post-Fundoplication Paraesophageal Hernia in Children
type: item
description: Purpose: Migration of Nissen fundoplication to the thorax is a frequent complication of antireflux surgery. Occurring in up to 12% of children. Achieving adequate intra-abdominal esophageal length requires dissection of the phrenoesophageal membrane. The primary objective of this study was to assess the effectiveness of phrenoesophageal membrane reconstruction in preventing thoracic migration of the fundoplication in children undergoing laparoscopic surgery. Methods: Retrospective cohort study of 690 children undergoing laparoscopic fundoplication, Group A without membrane reconstruction, and Group B with membrane reconstruction. The outcome was intrathoracic migration of the postoperative fundoplication. Odds ratio (OR) and 95% confidence intervals (CI) were calculated with p ≤ 0.05. Results: A total of 631 patients met inclusion criteria, 52.1% in Group A and 47.9% in Group B. Intrathoracic migration occurred in 7.0% in Group A and 1.3% in Group B (p < 0.001). Phrenoesophageal reconstruction in Group B resulted in an 82.1% reduction in the likelihood of migration (OR 0.179; 95% CI: 0.06-0.52). Conclusion: This study highlights the need to perform a reconstruction of the phrenoesophageal membrane when performing a fundoplication in children, which significantly reduces the intrathoracic migration of fundoplication.
subject: Articles
  topic: section
subject: Nissen Fundoplication, Intrathoracic Migration, Gastroesophageal Reflux, Phrenoesophageal Membrane
  topic: keywords
creator: Carlos García-Hernández
creator: Diego Leonardo Herrera-Ojeda
creator: Ariadna Alvelais-Arzamendi
creator: Sergio Landa-Juárez
creator: Carlos Aguilar-Gutiérrez
creator: Lourdes Carvajal-Figueroa
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-03-24
publication date: 2026-03-24
starting page: 1
ending page: 5
doi: 10.47363/JPRRR/2026(8)197

From Adverse Childhood Experiences to Digital Trauma-Informed Care: Rethinking Prevention Infrastructure for Pediatric and Population Health
type: item
description: The Adverse Childhood Experiences (ACE) Study established a durable association between early adversity and long-term health risk. What has proven more difficult is translating that insight into consistent prevention practice within pediatric and community systems. While ACE scores quantify exposure, they do not fully capture how long stress responses remain active after adversity occurs. Emerging work in stress physiology suggests that the duration of stress activation may represent a clinically meaningful and potentially modifiable target. This paper revisits ACE science through that lens and examines whether digitally delivered trauma informed supports can serve as scalable components of prevention infrastructure. Drawing from research on stress regulation, Positive Childhood Experiences (PCEs), and Mind–Body interventions, we propose that reducing stress persistence-particularly during childhood-may offer a pragmatic strategy for improving long-term health trajectories while easing system burden.
subject: Articles
  topic: section
subject: Childhood
  topic: keywords
subject: Digital Trauma
  topic: keywords
subject: Population Health
  topic: keywords
creator: Brian M Alman
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-03-17
publication date: 2026-03-17
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2026(8)196

A Retrospective Analysis of Clinic Epidemiological Features and Treatment Outcomes of Renal Cell Carcinoma University
type: item
description: Background: Renal cell carcinoma (RCC), the predominant form of kidney cancer, represents a significant health burden due to its varied epidemiology, complex molecular biology, and challenging prognosis. Patients and Methods: This retrospective study explores the clinic epidemiological features and treatment outcomes of RCC cases managed in the Clinical Oncology Department of Ain Shams University from January 2018 to December 2023. Results: Epidemiological data revealed that RCC is more prevalent in males and typically diagnosed in later stages, often incidentally during imaging for unrelated health issues. We analyzed the demographic, clinical, and pathological characteristics, treatment approaches-including surgical and systemic therapies-and survival outcomes of the study cohort. Key factors affecting progression-free survival (PFS) and overall survival (OS) were examined, with an emphasis on emerging therapies and the integration of prognostic models such as the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) criteria. Findings underscore the efficacy of targeted therapies and immunotherapy, which have markedly improved outcomes for advanced RCC. Conclusion: This study concludes that RCC is a complex malignancy with significant variation in outcomes depending on factors such as tumour stage, histology, and treatment modality. Surgical resection remains the gold standard for curative treatment, with the potential for long-term survival, particularly in early-stage disease. However, the systemic treatment landscape for renal Cell Carcinoma (RCC) has dramatically evolved over the past decade with the introduction of targeted therapies. Targeted therapies like Sunitinib and Pazopanib continue to play a critical role especially in less developed countries due to financial problem and limitation to receive immunotherapy. Continued research and advancements in treatment strategies are essential for improving survival rates and quality of life f…
subject: Articles
  topic: section
creator: Zizit Hamdi Mohammed El-Shahawi
creator: Soheir Sayed Ismail
creator: Nesreen Ahmed Mosalam
creator: Lamiaa Moustafa Abdel Megied
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-02-27
publication date: 2026-02-27
starting page: 1
ending page: 10
doi: 10.47363/JPRRR/2026(8)191

Clinical and Genetic Characterization of Late-Onset Pompe Disease in an Adolescent Carrying a Rare GAA Coding Mutation
type: item
description: Background: Pompe disease (Glycogen Storage Disease Type II) is a rare autosomal recessive neuromuscular disorder caused by acid α-glucosidase (GAA) deficiency. Late-onset Pompe disease (LOPD) exhibits variable clinical presentations, often delaying diagnosis. Case Report: We describe a 12-year-old male presenting with progressive proximal lower limb weakness, exercise intolerance, and persistent hyperCKemia. Neurological examination revealed macroglossia and mild proximal hypotrophy. EMG showed a myopathic pattern. Biochemical testing revealed markedly alfa, resulting in modest functional improvement. reduced GAA activity, and genetic analysis confirmed compound heterozygosity for c.2480_2426del (rare frameshift) and c.-32-13T>G (common LOPD splicing mutation). Pulmonary assessment indicated diaphragmatic weakness. The patient was initiated on enzyme replacement therapy with avalglucosidase Conclusion: This case highlights the importance of early recognition, enzymatic testing, and genetic confirmation in pediatric LOPD, particularly in patients harboring rare or underreported mutations.
subject: Articles
  topic: section
subject: Pompe Disease, Glycogen Storage Disease Type II, Genetic Mutation, Neuromuscular Disorders, Case Report, Enzyme Replacement Therapy
  topic: keywords
creator: Maria Elena Meza Cano
creator: Verónica Ivonne López Diaz
creator: Ana Carolina Aguilar Venegas
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-02-21
publication date: 2026-02-21
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2026(8)195

Salvage Re-Irradiation after Complex Treatment in Childhood Leptomeningeal Metastatic Medulloblastoma-Clinical Case withLiterature Review
type: item
description: Leptomeningeal metastases diagnosed in a child with high-risk medulloblastoma immediately after surgery are very rare. The primary treatment is extremely complicated, namely the assessment of the duration of systemic and intraventricular chemo- and immunotherapy, as well as the timing of starting craniospinal radiotherapy. Even more complicated is the question “When in time, in what volume and with what cumulative doses should salvage re-radiotherapy be performed in a child with long-term observed leptomeningeal spread diagnosed immediately after the initial surgery?”. Based on a clinical case of a child with high-risk medulloblastoma and a literature review, we aim to answer the above questions.
subject: Articles
  topic: section
subject: Leptomeningeal Metastases
  topic: keywords
subject: High-Risk Medulloblastoma
  topic: keywords
subject: Salvage Re-Radiotherapy
  topic: keywords
subject: Leukoencephalopathy
  topic: keywords
subject: Subacute Radiation Neurotoxicity
  topic: keywords
creator: Lena Marinova
creator: Vaska Vasileva
creator: Nikolay Kahchiev
creator: Nadezhda Tsvetkova
creator: Katia Sergieva
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-01-30
publication date: 2026-01-30
starting page: 1
ending page: 7
doi: 10.47363/JPRRR/2026(8)193

Pediatric Psychology: Understanding the Mind of a Growing Child
type: item
description: Pediatric psychology is a specialized branch of psychology that focuses on the emotional, behavioral, and developmental well-being of children from infancy through adolescence. It bridges two worlds-medicine and psychology-to ensure that a child’s mental health is understood within the context of their physical health, family environment, and social experiences.
subject: Articles
  topic: section
subject: Pediatric Psychology
  topic: keywords
subject: Growing Child
  topic: keywords
creator: Nadia Suhail
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-01-03
publication date: 2026-01-03
starting page: 1
ending page: 2
doi: 10.47363/JPRRR/2026(8)190

Long-Term Evaluation of Supracondylar Fractures of the Humerus (SHF) in Elbow Extension in Children at the Pediatric Surgery Department of the Aristide Le Dantec University Hospital Centerin Dakar
type: item
description: Objective: The aim of this study was to evaluate the surgical management of extension supracondylar fractures of the elbow in children at the pediatric surgery department of the Aristide Le Dantec University Hospital. Patients and Methods: This was a retrospective, descriptive, single-center study conducted over a 5-year period from January 1, 2020, to December 31, 2024, at the pediatric surgery department of the Aristide Le Dantec University Hospital in Dakar. The study included all patients under 16 years of age with a recent extension supracondylar fracture of the humerus (occurring within 21 days) requiring surgical intervention, with a 3-year follow-up. Results: A total of 24 patients agreed to participate in our 3-year evaluation study. The mean age was 6.12 ± 3.34 years. The distribution was 17 boys and 7 girls. 71% were classified as type IV, compared to 29% as type III. Open surgery with a posterior approach and internal cross-shaped pinning was performed in 91.6% of cases, compared to 8.4% for percutaneous pinning using the Judet method. The mean length of hospital stay was 10 days. Removal of the osteosynthesis hardware was performed in the majority of cases between 45 and 90 days. Postoperative complications included one case of vascular injury, three cases of surgical site infection, one case of forearm compartment syndrome, and four surgical revisions. With a mean follow-up of 36 months, we observed joint stiffness in 19 cases, including six cases of stiffness greater than 50 degrees, seven cases of stiffness between 20 and 50 degrees, and six cases of stiffness less than 20 degrees. Axial deviation was observed in 11 patients, including six cases of cubitus varus (25%) and five cases of cubitus valgus (20.8%). Nine cases (37.5%) of disfiguring hypertrophic scarring were observed. According to the Marion-Lagrange criteria, the results were satisfactory in 75% of cases. Conclusion: Open surgery for supracondylar fractures of the humerus is the most freq…
subject: Articles
  topic: section
subject: Leptomeningeal Metastases
  topic: keywords
subject: High-Risk Medulloblastoma
  topic: keywords
subject: Subacute Radiation Neurotoxicity
  topic: keywords
subject: Leukoencephalopathy
  topic: keywords
subject: sLeukoencephalopathy
  topic: keywords
creator: Camara Souleymane
creator: Diop Aly
creator: Sy Fatou
creator: Sabounji Mohamed Salsabil
creator: Ndour Oumar
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-01-30
publication date: 2026-01-30
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2026(8)194

A Horseshoe Appendix Duplex in Pediatrics: Do Not Misdiagnosethis Anatomical Anomaly!
type: item
description: Introduction: Horseshoe appendix duplex is an extremely rare anomaly with 16 cases de-scribed worldwide. The objective of this work is to bring the 17th global case and to do a re-view of the literature. Case Report: A 15-year-old boy, received for acute appendicitis. The abdominal ultrasound revealed acute appendicitis with a small collection around. Surgery was performed and we found a horseshoe appendix in the right iliac fossa with the two bases, each communicating with the cecum. Histological examination confirmed the digestive origin of the duplex appen-dix with the four typical histological layers. Conclusion: The horseshoe shape is the rarest of appendicular duplications. It is most often discovered during appendectomies.
subject: Articles
  topic: section
subject: Horseshoe Appendix Duplex, Pediatric
  topic: keywords
creator: Camara Souleymane
creator: Ndoye Jean-Marc Ndiaga
creator: Seye Cheikh
creator: Ndour Oumar
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-01-30
publication date: 2026-01-30
starting page: 1
ending page: 2
doi: 10.47363/JPRRR/2026(8)192

Interleukin-10 Gene Expression Predicts Response to Therapy in Childhood Acute Lymphoblastic Leukemia
type: item
description: Several studies have demonstrated that IL-10 have been associated with therapy outcome in hematological malignancies. IL-10 might therefore also correlate with clinical outcome in childhood acute lymphoblastic leukemia (ALL). In addition to expressing full-length IL-10, a new splicing-derived IL-10 variant (termed IL-10δ3) can be detected in ALL samples. These isoforms generally have different affinities to their receptors, contributing to generating important function in modulating the biologic activity of normal IL-10. Most childhood malignancies lack reliable and specific biochemical tumor markers correlating with disease extent and aggressiveness. That is why several non-specific indirect indicators, including ESR, CRP and LDH, are used in common practice as additional diagnostic and prognostic tools. The study presented here aimed to assess whether the expression of IL-10 and its isoform, IL-10δ3 correlate with other prognostic factors. Mainly, the response to treatment and risk of relapse in 60 children with B-cell precursor (BCP)-ALL, treated at the Pediatric Oncology Department, National Cancer Institute, Cairo University and Damnhour Teaching hospital (DMNI) during the time period from August 2009 to May 2014 according to NCI protocols modified from the St. Jude Total XV protocols. The median age of the patients was 6 years (range, 0.91 years to 24 years) and the male: female ratio was 1.61:1 (37 males and 23 females). Study data showed a possible role of IL-10δ3 particularly decreased incidence of relapse and prolonged event-free survival in first complete remission, whereas no association between response to therapy and IL-10 and IL-10 isoform, IL-10δ3, expression. Moreover, CD34 expression with a good prognosis was higher in patients displaying IL-10δ3 expression compared to patients not expressing the isoform. Results revealed correlation between pro-B stage and IL-10δ3 expression (the 4 patients with pro-B stage expressed IL-10δ3). This relation was no…
subject: Articles
  topic: section
subject: Interleukin
  topic: keywords
subject: Childhood Acute Lymphoblastic Leukemia
  topic: keywords
creator: Aisha Areaby Sehari Gammodi
creator: Ashraf Mohamed Ayad
creator: Emad Nabil Ebied
creator: Amal Younan Abd El Malek
creator: Nada Mohamed Fadel
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2026-01-19
publication date: 2026-01-19
starting page: 1
ending page: 12
doi: 10.47363/JPRRR/2026(8)189

Screening of Helicobacter Pylori in Symptomatic Libyan Children
type: item
description: Helibacobater (H. pylori) is among the most common bacterial infection in humans The prevalence of H. pylori varies markedly between countries. In Libya we have not a good ideas about the the epidemiology in children. (H. pylori) is usually associated with peptic ulcer disease and gastric carcinoma.Typically, children get infected during the first decade of life, but diseases associated with H. pylori are seen mainly in adults. Since evidence from the literature postulates that H. pylori infection occurs mostly during childhood. Studying the epidemiology of this infection in pediatric patients can enable better understanding of the risk factors and consequences of infection. Multiple diagnostic methods are available for the detection of H. pylori infection.The aim of this study was to use non-invasive method (IgG serology) for diagnosis of H. pylori infection in a prospective observational study conducted among 130 children from May 2022 to May 2025 symptomatic children mainly complaining of recurrent abdominal pain, between two and eighteen years of age. attending outpatient clinic in Gharyan Teaching Hospital. IgG antibodies were measured in these patients’ sera using a commercially available enzyme linked immunosorbent assay (ELISA). H. pylori IgG antibodies were concordant in the general proportion of H. pylori infection for both male and female were 29%, 73% of infected children by H. pylori were males, 80% of H. pylori infected children were > 8 years old.
subject: Articles
  topic: section
subject: H. Pylori
  topic: keywords
subject: Abdominal Pain
  topic: keywords
subject: Epidemiology
  topic: keywords
creator: Aisha Areaby Sehari Gammodi
creator: Fathia Hameda Ben Saleh Fathia Hameda Ben Saleh
creator: Farag Abussalam Ahmed Farag Abussalam Ahmed
rights: Copyright (c) 2025 Journal of Pediatrics Research Reviews & Reports
date: 2025-12-12
publication date: 2025-12-12
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2025(7)188

Six Years Old Boy with Post Covid-19 Isolated Palatal Paralysis, A Rare Clinical Case
type: item
description: Unilateral acquired isolated palatal paralysis is rarely seen in COVID 19 children with unclear pathogenesis. Post-infectious immune-associated cranial mono-neuropathy is a suggestive theory. Cases due to trauma, tumor, and brainstem lesions have been also reported. The presentation is usually nasal regurgitation and uvular deviation. A case report of acquired isolated palatal palsy in a 6 years old boy is presented below with a good response to treatment.
subject: Articles
  topic: section
subject: Paralysis
  topic: keywords
subject: Vagus
  topic: keywords
subject: Palatal
  topic: keywords
subject: COVID-19
  topic: keywords
creator: Nashaat Elsayed Farara Nashaat Elsayed Farara
creator: Nafea Almutairi Mohammad
creator: Hatem Ibrahim Elsarnagawe Ibrahim Elsarnagawe
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-11-14
publication date: 2025-11-14
starting page: 1
ending page: 2
doi: 10.47363/JPRRR/2025(7)187

Insight into Down Syndrome and its Rehabilitation
type: item
description: Down syndrome (DS), also known as trisomy 21, is a well-characterized genetic disorder caused by an extra copy of chromosome 21, leading to developmental delays, congenital anomalies, and intellectual disability. Despite significant scientific advances in identifying its chromosomal basis and risk factors, the precise cause of nondisjunction during meiosis remains unknown, limiting our understanding of its true origins. This incomplete understanding also contributes to suboptimal treatment outcomes. However, according to the teachings of Guan Yin Citta Dharma Door (心灵法门), DS is not merely a genetic condition but a karmic manifestation arising from unresolved spiritual debts, ancestral karma, or spiritual possession. This study presents seven responses from Dharma Master Jun Hong Lu to inquirers, which clarify the karmic causes of DS and propose Buddhist-based solutions, such as spirit ascension and karma elimination. Additionally, we highlight four real-world cases where families of children with DS applied these Golden Buddhist Practices, resulting in incredible documented improvements in behavior, cognition, and overall health. These outcomes suggest that DS may be more accurately understood as a karmic condition with limited physical genetic expression. This perspective explains why Dharma-based practices can yield extraordinary therapeutic effects in children with DS.
subject: Articles
  topic: section
subject: Guan Yin Citta Dharma Door
  topic: keywords
subject: Golden Buddhist Practices
  topic: keywords
subject: Karma
  topic: keywords
subject: Spirits
  topic: keywords
subject: Down Syndrome
  topic: keywords
subject: Trisomy 21
  topic: keywords
subject: Recovery
  topic: keywords
creator: Xinghong Yang Xinghong Yang
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-10-21
publication date: 2025-10-21
starting page: 1
ending page: 12
doi: 10.47363/JPRRR/2025(7)182

Covariates of Maternal Health Care Utilization: Evidence from Agricultural Households in Rural Nigeria
type: item
description: Maternal health care utilization remains a persistent public health concern in Nigeria, particularly in rural areas where maternal mortality rates are among the highest globally. This study investigates the socio-economic and demographic covariates influencing maternal health care utilization among agricultural households in rural Nigeria. Using data from the 2018 Nigeria Demographic and Health Survey (NDHS), the analysis focused on 2,751 women in agricultural households, employing a Tobit regression model. The findings reveal that maternal health care utilization is significantly influenced by factors such as mother’s education, age at first birth, employment type,media exposure, household head’s sex, regional location, and birth order. Contrary to prior studies, the study found that formal education, media exposure, and full-time engagement in agriculture were negatively associated with maternal health care utilization, suggesting underlying sociocultural barriers. For instance, religious and patriarchal norms in some northern regions were noted to limit women’s autonomy in health-seeking decisions. The study also affirms regional disparities, with women in the South-East and South-West zones less likely to utilize maternal care compared to those in the North-Central zone.The study concludes that maternal health care utilization in rural agricultural households is shaped by intersecting social, economic, and cultural factors.Addressing these determinants is vital for improving health outcomes and enhancing household productivity in Nigeria’s rural economy. The results underscore the need for multi-sectoral policy approaches that promote female education, delay early marriage, improve healthcare infrastructure in rural areas, and economically empower women. Additionally, targeted media campaigns and male involvement in maternal health decisions are crucial for fostering behavioral change and boosting service uptake. Addressing these barriers is crucial not only for…
subject: Articles
  topic: section
subject: Maternal Health
  topic: keywords
subject: Maternal Education
  topic: keywords
subject: Household Wealth
  topic: keywords
subject: Maternal Autonomy
  topic: keywords
subject: Poverty Reduction
  topic: keywords
creator: Mobolaji Adejoorin Victoria
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-09-30
publication date: 2025-09-30
starting page: 1
ending page: 5
doi: 10.47363/JPRRR/2025(7)181

Phenotypic Spectrum and Diagnostic Challenges in Non-21-Alfa-Hydroxylase Deficiency Congenital Adrenal Hyperplasia: A Case Series from a Tertiary care Centre
type: item
description: Purpose: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder caused by enzyme deficiencies in adrenal steroidogenesis, with 21-hydroxylase deficiency (21-OHD) being the most common. However, rarer forms such as 11β-hydroxylase (11β-OHD), 3β-hydroxysteroid dehydrogenase type 2 (3β-HSD2), 17α-hydroxylase (17α-OHD), and steroidogenic acute regulatory protein (StAR) deficiency present diagnostic challenges due to variable phenotypes. This study describes the clinical, biochemical, and genetic profiles of non-21OHD CAH cases at a tertiary care centre. Methods: A retrospective review of 87 CAH patients from 2008 to 2022 identified 13 cases of non-21OHD CAH. Clinical, biochemical, imaging and genetic data were analysed. The diagnosis was confirmed by hormonal assays and next-generation sequencing (NGS)-based genetic analysis. Results: Among the 13 cases, six patients had 11β-OHD, primarily presenting with precocious puberty, hypertension, and hyperpigmentation, with elevated ACTH, 17-OHP, and suppressed renin levels. Three patients with 3β-HSD2 deficiency were diagnosed in early infancy following salt-wasting crises. 17α-OHD was diagnosed in three adolescent females presenting with primary amenorrhea, tall stature, hypertension, and elevated gonadotropins.One case of StAR deficiency was diagnosed at 45 days of life, presenting with adrenal crisis and severe adrenal insufficiency. Conclusion: Non-21OHD CAH presents diagnostic challenges due to its varied clinical spectrum. Hypertension and hypokalemia are key differentiators for 11β-OHD and 17α-OHD, while steroid profiling (LC-MS) aids in diagnosing 3β-HSD2 deficiency. However, the most crucial aspect is the early diagnosis, which is a significant factor in preventing complications like hypertensive cardiomyopathy and adrenal crises.
subject: Articles
  topic: section
subject: Non-21-OHD CAH
  topic: keywords
subject: Congenital Adrenal Hyperplasia
  topic: keywords
subject: Genetic Disorders
  topic: keywords
subject: Young Hypertension
  topic: keywords
creator: Shriraam Mahadevan
creator: Anand Sheya
creator: Vasireddy Nayana Tara
creator: Asha Ranjan
creator: Adlyne Reena Asirvatham
creator: Sai Namratha Gogineni
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-04-28
publication date: 2025-04-28
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2025(7)177

A Parasitic Twin Diagnosed Prenatally As a Sacrococcygeal Teratoma: A Case Report
type: item
description: Parasitic twinning is a rare entity. It is an asymmetric conjoined twinning in which a poorly formed twin, known as the parasite, is attached to a fully developed co-twin, known as the autosite. The parasite depends on the autosite for blood supply. It is diagnosed prenatally with ultrasound, and treatment involves resection of the parasite postnatally. We describe a case that was prenatally diagnosed on 2D ultrasound as a sacrococcygeal teratoma at 25 weeks.No other anomaly was detected. Caesarean delivery was conducted at 34 weeks on account of failure to progress following spontaneous preterm labour.At delivery, we found that the sacrococcygeal mass was a parasitic twin with a poorly formed body, lower limb, and hair. These fetal components were not demonstrated on the prenatal 2D ultrasound. Postnatal assessment revealed no other abnormality. The mass was successfully resected on day 3 of life. The resection was done early on account of ulceration of the mass/ parasite. The histopathological assessment revealed more fetal parts, including brain tissue and lungs. Prenatal diagnosis is essential as it identifies associated anomalies and helps with prognostication and planning of obstetric and surgical management by a multidisciplinary team.
subject: Articles
  topic: section
subject: Parasitic Twinning
  topic: keywords
subject: Prenatal Diagnosis
  topic: keywords
subject: 2D Ultrasound
  topic: keywords
subject: Multidisciplinary
  topic: keywords
creator: Jeff Osei Agyapong
creator: Victor Etwire Victor Etwire
creator: Alim Swarray-Deen Alim Swarray-Deen
creator: Jerry Coleman
creator: Kawku Doffour-Dapaah
creator: Alex K Boateng
creator: Perez Sepenu
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-07-30
publication date: 2025-07-30
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2025(7)186

Neurodevelopmental Outcome of High-Risk Neonates At 24 Months of Age, With Respect to General Movements of Prechetl at Term or Within 3 Months of Age
type: item
description: Background: Advances in secondary and tertiary level neonatal care in India and the state of Kerala have resulted in better survival and reduction of mortality of high risk neonates. So it is essential to have follow up of these babies more frequently and start early interventions to prevent or reduce the severity of developmental delay. Various non- invasive, cost effective methods are being tried to detect or predict early the developmental delay, one among these methods is general movements of Prechetl, since only a small percentage of neonates with risk factors are developing significant developmental delay later. Methods: Neonates 25 weeks and above, but less than 42 weeks, admitted with risk factors and discharged, presenting for follow up within 3 months of age were enrolled for the study. Those babies having visible birth defects (VBD), chromasomal or other genetic disorders, and dysmorphic or syndromic features were excluded from the study. Neonates at term or their first visit within 3 months were observed for general movements of Prechetl when the baby is remaining alert without crying and noted as normal or absent/abnormal. These high risk babies (N=375) in this prospective observational analytic study were followed up to their completed or corrected 24 months of age. Neurodevelopmental assessment done in domains- cognitive, communication, motor, and social-emotional at 24 months using Bayley scales of infant and toddler development edition-3 (BSID-III). The study was conducted over a period of 6 years from 2017 in south of middle Kerala, India. Results: Out of total 375 high risk babies, 53 babies were having abnormal/absent general movements pattern of Prechetl and 322 had normal general movements pattern. High risk babies with absent/abnormal general movements cohort babies were having significantly lower total and domain-wise (cognitive, language, motor and social-emotional) developmental scores compared to high risk babies with normal general moveme…
subject: Articles
  topic: section
subject: Cerebral Palsy
  topic: keywords
subject: Developmental Delay
  topic: keywords
subject: General Movements of Prechetl
  topic: keywords
subject: High Risk Newborn
  topic: keywords
subject: Neurodevelopmental Outcome
  topic: keywords
creator: Jayakumar PR Jayakumar PR
creator: Sukumaran PS
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-06-15
publication date: 2025-06-15
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2025(7)183

Immature Intracranial Teratoma in Childhood - A Rare Clinical Case from Our Practice
type: item
description: Immature teratomas are rare intracranial malignant tumors of childhood, predominantly localized in the pineal or suprasellar brain region. We present a rare clinical case of a 12-year-old boy with an immature intracranial teratoma who underwent apparently total tumor excision followed by local cranial radiotherapy. The presented clinical case focuses on the diagnosis and complex treatment of these rare non-germ cell brain tumors in childhood. A strict pathohistological diagnosis, serum and cerebrospinal fluid tumor marker testing (AFP and HCG), and MRI of the craniospinal axis are required.
subject: Articles
  topic: section
subject: Immature Intracranial Teratoma
  topic: keywords
subject: Childhood
  topic: keywords
subject: Complex Treatment
  topic: keywords
subject: Surgery
  topic: keywords
subject: Chemotherapy
  topic: keywords
subject: Radiotherapy
  topic: keywords
creator: Lena Marinova
creator: Vaska Vasileva
creator: Nikolay Kahchiev
creator: Nadejda Tsvetkova
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-06-15
publication date: 2025-06-15
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2025(7)179

Assessing the Effectiveness of HIV Counseling and Testing Programs: A Retrospective Study at an Apex Regional STD Centre in North India
type: item
description: Background: HIV counseling and testing are foundational in the fight against HIV/AIDS, offering opportunities for prevention, early diagnosis, and treatment linkage. This study evaluated the effectiveness of HIV counseling and testing services at an Apex Regional STD Centre in North India. Methods: A retrospective observational study was conducted from January to December 2023. Data were extracted from center registers, including the number of individuals receiving pre-test counseling, undergoing HIV testing, and testing positive. Partner engagement, HIV transmission routes, age and gender distribution, and referral of suspected TB cases were also analyzed. Quality indicators such as counseling completeness, content delivered, and partner notification services were reviewed. Results: A total of 29,017 individuals received pre-test counseling, with 28,609 undergoing HIV testing (98.59% uptake). HIV positivity was highest among individuals aged 35–49 years (2.13%). Heterosexual contact with casual partners in males and regular partners/spouses in females were the most reported transmission routes. Among 389 partners tested, 180 were HIV-positive (46.3%). However, only 230 partners (59.1%) received formal counseling. The TB referral system identified sputum-positive TB in 0.10% of referred clients. Counseling session quality was adequate in 85% of cases based on adherence to national counseling guidelines. Conclusion: HIV counseling and testing services at the center demonstrated high uptake and significant case detection. However, gaps in partner counseling and data tracking limit the full evaluation of program effectiveness. Strengthening partner services, standardizing counseling quality audits, and integrating follow-up mechanisms are critical for enhancing outcomes.
subject: Articles
  topic: section
subject: HIV Counseling
  topic: keywords
subject: HIV Testing
  topic: keywords
subject: Partner Services
  topic: keywords
subject: TB-HIV Co-Infection
  topic: keywords
subject: India
  topic: keywords
subject: Public Health
  topic: keywords
subject: STD Clinic
  topic: keywords
creator: Niti Khunger
creator: Abhay Goyal
creator: Abhishek Lachyan
creator: Sumathi Muralidhar Sumathi Muralidhar
creator: Anshuman Dash Anshuman Dash
creator: Sanjay Kumar
creator: Harsh Madhavi
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-05-30
publication date: 2025-05-30
starting page: 1
ending page: 2
doi: 10.47363/JPRRR/2025(7)178

Metabolic Characteristics in Obese Children
type: item
description: Introduction: Metabolic syndrome is one of the complications of obesity with a significant impact on health. This MS is diagnosed according to the International Diabetes Federation 2007 in children aged 10 to 16 years with waist circumference > 90th percentile according to the curves of McCarthy and two of the following metabolic characteristics: HDL C < 40 mg/dL, TG≥150 mg/dL, blood glucose ≥ 100 mg/dL and blood pressure≥130/85mmHg. Goals: We performed a retrospective and prospective study at the pediatric obesity consultation. The main objective is to assess the metabolic syndrome in a population of obese children and adolescents. The secondary objectives are the evaluation of the various criteria of the metabolic syndrome, and the impact of the degree of obesity, the search for comorbidities and their repercussions, and finally the evaluation of the care. Results: The survey involved 74 children and adolescents,from January 2011 to December 2021. The frequency of metabolic syndrome is 35.1%.with an average age around puberty of 12.92 years. There is no significant difference in frequency by sex. This frequency increases with the degree of obesity Insulin resistance remains the first factor responsible for the genesis of MS, Dyslipidemia affects more than a third of these children. Arterial hypertension is noted in 14% of subjects.For glycemic abnormalities, 16.21% of children have fasting hyperglycemia. For complications the non alcoholic fatty liver disease NAFLD affects approximately 33% of these children, the obstructive sleep apnea OSA was only confirmed in 4% of these children.
subject: Articles
  topic: section
subject: Obese Children
  topic: keywords
subject: metabolic syndrome
  topic: keywords
subject: type 2 diabetes
  topic: keywords
subject: dyslipidemia
  topic: keywords
subject: metabolic abnormalities
  topic: keywords
creator: Assia Cherfaoui Assia Cherfaoui
creator: Amel Hadji Amel Hadji
creator: Rachida Boukari
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-04-05
publication date: 2025-04-05
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2025(7)184

Standardization of Viral Neutralization Assay Used in To the Determination of Neutralizing Antibodies in the Evaluation Studies of the Cuban Vaccines against COVID-19
type: item
description: The epidemiological situation created by SARS-CoV-2 imposed the challenge of developing vaccines and demonstrating their efficacy through a test capable of detecting functional neutralizing antibodies. It was proposed to standardize of viral neutralization assay used in the determination of neutralizing antibodies in the evaluation studies of the Cuban vaccines against COVID-19. Serial doubling dilutions of the serum samples were used and mixed with equal volumes of strain D614G at different infective doses an concentrations of Vero E6. The neutralization titer was determined by the colorimetric method and the cytopathic effect. 24 hours were defined as virus harvest time, the fourth day as the optimal time for reading the assay, 2x104 cells/well as cell concentration, and 100 TCID50 as optimal infective dose. The analytical specificity was 100%, as well as the specificity and diagnostic sensitivity. There was a high correlation between the micro neutralization assay and the UMELISA anti RBD system and a strong association with the molecular neutralization test. There were no differences between the cytopathic effect readings between the two reading methods. It was shown that it is a sensitive, specific and precise method, which guarantees the feasibility of its use in the evaluation of vaccine candidates against COVID-19.
subject: Articles
  topic: section
subject: SARS-CoV-2
  topic: keywords
subject: Viral Neutralization Assay
  topic: keywords
subject: Standardization
  topic: keywords
creator: Enrique Noa Romero Enrique Noa Romero
creator: Yaday Alfonso Mirabal Yaday Alfonso Mirabal
creator: Yanicet Rosell la Rosa
creator: Danay Carrillo Valdes Danay Carrillo Valdes
creator: Gretel Susana Pérez Bartutis
creator: Mireida Rodríguez Acosta
creator: Dayami Martin Alfonso
creator: Nibaldo Luis González Sosa
creator: Yanin Hernández Rodríguez Yanin Hernández Rodríguez
creator: Yenicet Infante Hernández
creator: Anamary Suárez Batista
creator: Marta Dubed Echevarria
creator: María Teresa Pérez Guevara
creator: Juliet María Enriquez Puertas
creator: Otto Cruz Sui
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-03-25
publication date: 2025-03-25
starting page: 1
ending page: 7
doi: 10.47363/JPRRR/2025(7)185

Does Simultaneous Intensity Modulated Radiotherapy with Temozolomide Increase the Radiosensitivity of Childhood Diffuse Intrinsic Pontine Glioma (DIPG)?- a Clinical Case from our Practice
type: item
description: Diffuse intrinsic pontine glioma (DIPG} is a high-grade glioma (HGG) that originates in the pons and is seen almost exclusively in children. The healing results achieved after a self -conducted conventional, hyperfractionated and hypofractionated radiotherapy (RT) up to a total tumor dose of 54 Gy at DIPG are unfavorable. We present our observations in a child with a locally advanced DIPG after a conventional concomitant Temozolomide radiotherapy. In order to increase the survival in this clinical case, we decided to conduct a simultaneous Temozolomide RT with an extended target volume with the inclusion of the ventricles. Two months after the Temozolomide intensity modulated radiotherapy (IMRT), the MRI reports a reduction in the tumor with a pronounced tumor necrosis, which is evidence of the radio -sensitization effect of Temosolomide.
subject: Articles
  topic: section
subject: Diffuse Intrinsic Pontine Glioma
  topic: keywords
subject: Childhood
  topic: keywords
subject: Intensity Modulated Radiotherapy
  topic: keywords
subject: Concomitant Temozolomide Radiotherapy
  topic: keywords
subject: MRI
  topic: keywords
creator: Lena Marinova Lena Marinova
creator: Vaska Vasileva
creator: Nikolay Kahchiev
creator: Spaska Kovacheva- Damyanova
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-02-10
publication date: 2025-02-10
starting page: 1
ending page: 7
doi: 10.47363/JPRRR/2025(7)176

Association between Breast Feeding and Development of Atopy
type: item
description: Background: Childhood atopic diseases are becoming more prevalent over time, making it an issue to investigate. One of the possible associated factors that has been studied is breastfeeding, which remains a controversial subject. A number of studies show a protective role of breastfeeding against atopic diseases such as asthma, allergic rhinitis, atopic dermatitis, food allergy, and others. However, other research could not find a positive relationship between breastfeeding and some types of allergies. Accordingly, we set out to investigate the relationship between breastfeeding and the development of atopy in our study. Methods: A hospital based cross-sectional study. The study was conducted in the Maternity and Children Hospital (MCH) in Hail region, between November 2022 and February 2023, targeting mothers with at least one child over the age of one month in the paediatrics and obstetrics/gynaecological clinics’ waiting areas and admission wards. Results: A sample of 423 children from Hail were studied in our research. Most of them were over twelve months old. Although most of the participants believed that breastfeeding reduces the incidence of atopic skin disease, the most prevalent type of feeding was formula feeding, followed by mixed feeding and exclusive breastfeeding. The study showed no significant effects of breastfeeding type on the development of allergies in children, as well as breastfeeding type and duration. However, there was a significant association between formula feeding and the development of allergic rhinitis, as it increases the incidence. Conclusion: The findings of this study demonstrated that no definitive link could be made between breastfeeding duration and the development of atopy or between breastfeeding type and the occurrence of atopy in children. However, the study shows that formula feeding is a significant risk factor for the development of allergic rhinitis.
subject: Articles
  topic: section
subject: childhood allergic diseases
  topic: keywords
subject: asthma
  topic: keywords
subject: atopic diseases
  topic: keywords
subject: food allergies
  topic: keywords
creator: Shog K Alahmed Shog K Alahmed
creator: Jumanah A Almuaili
creator: Safaa M Shaheen
creator: Raghad E Sultan
creator: Manar H Alshehri
creator: Manal N Alanazi
creator: Salma R Altamimy Salma R Altamimy
creator: Wijdan S Alsaad
creator: Areeb F Alshammari
creator: Reem A Alshammari
creator: Seeta S Alenezi
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2025-01-10
publication date: 2025-01-10
starting page: 1
ending page: 8
doi: 10.47363/JPRRR/2025(7)180

Long-Term Drug Treatment of a Giant Liver Hydatid Cyst in a Child
type: item
description: Background: Cystic еchinococcosis is a chronic parasitosis caused by the larvae of the tapeworm Echinococcus granulosus. Humans act as intermediate hosts and the larvae can affect any organ in the form of cysts. They are most often found incidentally by diagnostic imaging, where they have become large in size, with treatment being primarily invasive. Conservative treatment with albendazole is one of the appropriate treatment options, but it features a low success rate in cysts over 5 cm. Case Presentation: We describe a case of an 16-year-old girl with an active 12 cm cyst in the liver. Two consecutive courses with albendazole, with duration 3 months each, were conducted. The cyst reached a safe inactive stage and no relapses have been observed for 1 year since the last administration of the medication. Conclusions: Our experience shows that with large cysts albendazole courses may be extended including in childhood. Ultrasonography has clearly demonstrated its ability to follow-up patient in a cost effective manner and avoiding ionizing radiations.
subject: Articles
  topic: section
subject: Cystic echinococcosis (CE)
  topic: keywords
subject: tapeworm Echinococcus granulosus
  topic: keywords
subject: parasitic zoonosis
  topic: keywords
subject: hydatid cyst
  topic: keywords
creator: Valeri Velev Valeri Velev
creator: Valeri Velev
creator: Victoria G. Vicheva
creator: Yordanka Mitova-Mineva
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-12-20
publication date: 2024-12-20
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2024(6)179

Re-Feeding Syndrome as a Rare Sequelae Post Resolution of DKA
type: item
description: Refeeding Syndrome (RS) refers to electrolyte imbalances that occur in malnourished and abruptly refed patients. Though there is scarce evidence in pediatric literature, it is a potential life-threatening condition that can lead to organ dysfunction. It occurs when the body’s metabolism suddenly shifts from a catabolic state to an anabolic state which leads to rise in insulin secretion and electrolyte imbalances. Though is no clear definition of Refeeding syndrome, hypophosphatemia is considered as the hallmark of refeeding syndrome. We report the case of a 12 yr old male child, who recovered from diabetes ketoacidosis and as soon as enteral nutrition was initiated the child landed up in refeeding syndrome. Physicians should be aware about the risk factors leading to refeeding syndrome as prompt identification and initiation of treatment is the key to its management.
subject: Articles
  topic: section
subject: Refeeding syndrome (RS)
  topic: keywords
subject: adolescents
  topic: keywords
subject: anorexia
  topic: keywords
subject: American Society for Parenteral and Enteral Nutrition (ASPEN)
  topic: keywords
subject: DKA
  topic: keywords
creator: Renuka Patil
creator: Sajili Mehta
creator: Supriya Gupte
creator: Shailaja Mane Shailaja Mane
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-12-20
publication date: 2024-12-20
starting page: 1
ending page: 2
doi: 10.47363/JPRRR/2024(6)178

Shaping ASD Pathways: Early PT vs. Late Support for Neurodiversity
type: item
description: Autism Spectrum Disorder (ASD) is one of a several neurodevelopmental disorders. characterized by impaired social and communicative functioning, as well as repetitive and stereotypical patterns of behaviour and interests. Autism Spectrum Disorder (ASD) is characterized by challenges in social interaction, communication, and restricted or repetitive behaviours and interests [1]. ASD affects throughout an individual’s lifespan and has a very unique clinical picture due to its associated symptoms, which include hyposensitive or hypersensitive, hyperactivity, concentration and behaviour issues, and emotional, sleep, and mood abnormalities [2]. In the context of ASD, neurodiversity acknowledges that individuals on the autism spectrum have unique strengths, abilities, and ways of perceiving and interacting with the world, which are valuable and should be nurtured and supported.The DSM-5 criteria for ASD include persistent deficits in social communication and interaction, and restricted, repetitive patterns of behaviour, interests, or activities.
subject: Articles
  topic: section
subject: Autism Spectrum Disorder (ASD)
  topic: keywords
subject: DSM-5 criteria
  topic: keywords
subject: hypersensitive
  topic: keywords
subject: stereotypical patterns
  topic: keywords
creator: Maheshkumar Baladaniya
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-11-20
publication date: 2024-11-20
starting page: 1
ending page: 9
doi: 10.47363/JPRRR/2024(6)172

Therapies for Anterior Teeth Affected by MIH in Children and Adolescents: Two Case Reports
type: item
description: Molar and incisor hypomineralization (MIH) is a qualitative defect in enamel development affecting first molars and permanent incisors, characterized by well-limited opacities of different color. Affected incisors cause aesthetic concerns, particularly in young patients, and are usually the reason for consultation.To manage the aesthetics of these teeth, several treatment options are available. This article presents the management of two patients who came to the Pedodontics Department of the Mohammed VI Center for Dental Care for aesthetic concerns, related to the presence of opacities in the maxillary central incisors associated with MIH.
subject: Articles
  topic: section
subject: Hypo mineralization
  topic: keywords
subject: MIH
  topic: keywords
subject: Incisors
  topic: keywords
subject: Aesthetic treatment
  topic: keywords
subject: Infiltration resin
  topic: keywords
subject: ICON
  topic: keywords
subject: Microabrasion
  topic: keywords
subject: Aesthetic restoration
  topic: keywords
creator: Faid K
creator: El Omari Fz
creator: Bennour Z
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-10-30
publication date: 2024-10-30
starting page: 1
ending page: 4
doi: 10.47363/JPRRR/2024(6)174

Prevalence of Health Issues in Durres Children: Refractive Errors,Caries, and Scoliosis
type: item
description: This study evaluates the prevalence of three common health conditions refractive errors, dental caries, and scoliosis-among children aged 6-14 in Durrës, Albania. Recognizing that children’s health issues can have profound effects on their overall well-being and educational performance, this research aims to provide insights into the health needs of the pediatric population in this region. A total of 370 students from five different schools were assessed through a series of clinical screenings, dental evaluations using the Decayed, Missing, and Filled Teeth (DMFT) index, and postural examinations. The findings indicate significant variations in the prevalence of these conditions across different schools and between genders. Specifically, refractive errors were found to be more prevalent in boys, particularly myopia, which was observed more frequently at Vincenc Prendushi and Nënë Tereza schools. In contrast, hypermetropia and astigmatism demonstrated similar trends across both genders, highlighting the need for targeted vision screenings and interventions to mitigate these issues. The prevalence of dental caries was notably high at 42%, underscoring the urgent need for improved oral hygiene support, particularly among girls, who exhibited higher rates in some schools. Furthermore, scoliosis was identified in 12% of the assessed children, with a greater incidence among boys.Certain schools had notably higher prevalence rates, suggesting potential links to environmental factors such as classroom ergonomics and physical activity levels. This study emphasizes the importance of regular health screenings and educational interventions to address these prevalent conditions effectively.Additionally, the findings advocate for the development of targeted health policies aimed at improving children’s health outcomes, thereby promoting overall well-being and academic performance. By focusing on preventive measures and raising awareness about these common health issues, this rese…
subject: Articles
  topic: section
subject: Refractive Errors
  topic: keywords
subject: Dental Caries
  topic: keywords
subject: Scoliosis
  topic: keywords
subject: Prevalence
  topic: keywords
subject: Albania
  topic: keywords
creator: Marsida Krasniqi Marsida Krasniqi
creator: Rezarta Kalaja
creator: Aida Lako
creator: Selda Veizaj
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-10-30
publication date: 2024-10-30
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2024(6)175

Newborn COVID 19 Carriers: Experience from the Marrakech Neonatal Reanimation Department
type: item
description: Coronavirus 2019 (COVID-19) has spread rapidly around the world. Given the high rate of increased infection, the number of pregnant women and children affected by COVID-19 is consequently on the rise. Infection with SARS-CoV-2 is transmitted by droplets; other routes of transmission, although hypothesized, have not been confirmed. For the moment, it remains unclear whether and how SARS-CoV-2 can be transmitted from mother to fetus. Objective: to report on the experience of the neonatal intensive care unit in the management of covid 19-carrying newborns, and to provide documented information on mother-to-child transmission. This retrospective study examined the medical records of 22 newborns born to women with SARS-CoV-2 at university hospital Momamed VI in Marrakech. Of the 22 newborns, 9 had positive PCR test results for SARS-CoV-2; among their mothers, 15 had fever, seven had cough and 17 had given birth by caesarean section. The median term of birth was 37 weeks’ amenorrhea. Fifteen of the newborns were male. Most were asymptomatic. The evolution was marked in 2 newborns by worsening respiratory distress requiring intubation and sedation in one, with worsening and death in the setting of severe sepsis in the first and the second due to more than 30% involvement on chest CT with persistent signs of respiratory struggle. The rest of the patients progressed well under treatment, with no complications. Conclusion: Maternal-fetal transmission of the SARS-CoV-2 virus was not detected in the majority of reported cases, except in one neonate, although 9 of the 22 neonates tested positive for the SARS-CoV-2 PCR test. Our study supports the hypothesis that, although it rarely occurs, in utero vertical transmission of SARS-CoV-2 is possible.
subject: Articles
  topic: section
subject: Coronavirus
  topic: keywords
subject: Newborn
  topic: keywords
subject: Vertical Transmission
  topic: keywords
creator: Bennaoui Fatiha Bennaoui Fatiha
creator: Fadl Mrabih Rabou Maoulainine
creator: Soraa N
creator: El Idrissi Slitine Nadia
creator: Abi El AAla Khalid
creator: Abi El AAla Khalid Abi El AAla Khalid
creator: Lalaoui Abdessamad Lalaoui Abdessamad
creator: Lalaoui Abdessamad
creator: Bennaoui Fatiha
rights: Copyright (c) 2026 Journal of Pediatrics Research Reviews & Reports
date: 2024-10-21
publication date: 2024-10-21
starting page: 1
ending page: 3
doi: 10.47363/JPRRR/2024(6)173

Chemotherapy-Induced Febrile Neutropenia Managed on an Outpatient Basis at the Pediatric Hematology and Oncology Department of the Ibn Sina Children’s Hospital in Rabat
type: item
description: Introduction: Febrile neutropenia (FN) is an important cause of morbidity and mortality in patients with cancer. The general objective of this study was to collect data and analyze the factors influencing management of the febrile neutropenia at the day hospital at the pediatric department of Hematology and Oncology (SHOP) of Rabat. Patients and Methods: It was a cross-sectional study descriptive and analytical for a period of 3 months (from January 9 to March 31, 2017) which was made at the day hospital at the SHOP. The inclusion criteria were neutropenia (rate of the neutrophil account lower or equal to 500/mm3) and fever following a cure of cancer chemotherapy. Results: We have registered 43 cases of FN over a period of 3 months. The most affected age group was less than 5 years with a median age of 4 years and ranged from 0 to 15 years. The ALL accounted for 67.4%; 51% of patients lived between 100 and 299 km from the SHOP, and 76.7% of patients have made 1 to 6 hours to reach the SHOP. The median of the neutrophil rate was 100/mm3. Twenty cases (46.5%) had a rate of neutrophil account < 100/mm3 . Nine (20.9%) had signs related to infection. Twenty-five (58.1%) have been treated with mono antibiotic therapy, and 16 patients (37.2%) were treated with a bi antibiotic therapy. Fifteen cases (34.9%) were hospitalized for not getting the pyrexia after 72 h of antibiotic therapy.There were no deaths among hospitalized patients. Ninety three percent of the therapeutic education was made by the doctor. Bi-varied analysis showed that evolution depended on the depth of neutropenia. Conclusion: Outpatients treatment with febrile neutropenia at the day hospital is possible and must take account of the clinical status, isolation of patients and the neutrophil account. Education of patients and parents and stratification of cases are mandatory
subject: Articles
  topic: section
subject: Fever, Neutropenia, Antibiotic Therapy, Day Hospital
  topic: keywords
creator: Aissata Barry
creator: Aimee Kissou
creator: Abdoul Magib Cissé
creator: Laila Hessissen
creator: Mohammed Khattab
rights: Copyright (c) 2024 Journal of Pediatrics Research Reviews & Reports
date: 2024-09-30
publication date: 2024-09-30
starting page: 1
ending page: 6
doi: 10.47363/JPRRR/2024(6)167

Proximal Hamstring Avulsion through Growth Plate: Case Reportof an Innovative Solution with Early Return to Sports
type: item
description: Introduction: Proximal hamstring avulsion injuries significantly impact young athletes, particularly when involving growth plates. This case report and literature review aim to provide a comprehensive analysis of proximal hamstring avulsion through the growth plate, focusing on an innovative surgical solution designed to ensure early return to sports. Case Presentation: A 13-year-old male soccer player presented with acute posterior thigh pain following a match. Initial conservative management failed to relieve symptoms. Radiographic imaging and MRI confirmed a proximal hamstring avulsion through the growth plate. The innovative surgical intervention involved reattachment using two 2.5 mm triple-loaded soft anchors to avoid growth plate interference and potential future reinterventions. Postoperative rehabilitation included phased exercises starting with painfree mobility and progressing to strength training and sport-specific drills, leading to a full recovery within six months. Discussion: Surgical indications for hamstring avulsion include significant displacement of the avulsed fragment (>1-2 cm), conservative treatment failure, severe functional loss, and high-demand athletes requiring robust repair. Early MRI diagnosis, tailored surgical techniques avoiding growth plate disruption, and structured rehabilitation programs focusing on muscle balance and flexibility are crucial. Literature underscores the importance of early surgical intervention, as population-based studies show tailored rehabilitation reduces recurrence and improves functional outcomes. Conclusion: Proximal hamstring avulsion injuries in young athletes require meticulous diagnosis and treatment. The innovative use of soft anchors facilitates proper healing and early return to sports, highlighting the necessity for precise surgical techniques and comprehensive rehabilitation protocols. This integrated approach ensures optimal recovery, minimizes re-injury risks, and facilitates a safe return to h…
subject: Articles
  topic: section
subject: Hamstring
  topic: keywords
subject: Growth
  topic: keywords
creator: Bruno Capurro
creator: Sebastian Gonzalez -Vonder Meden
creator: Wilson Pizarro-Geraldo
creator: Eduardo Badillo-Pérez
creator: Carlos Cabrelles
creator: Francesco Vecchi
creator: Ignacio Muñoz
rights: Copyright (c) 2024 Journal of Pediatrics Research Reviews & Reports
date: 2024-08-12
publication date: 2024-08-12
starting page: 1
ending page: 7
doi: 10.47363/JPRRR/2024(6)166