Acute Liver Failure of unknown Origin in Pregnancy

Abstract

Acute liver failure (ALF) in pregnant women is one of the major public health issues and remains a challenging clinical problem
with extremely high maternal and fetal morbidity and mortality, which characterized by sudden onset of coagulopathy (international normalized ratio [INR] ≥ 1.5) and encephalopathy,may occur during pregnancy either as a pregnancy-associated etiology or an unrelated and coincidental liver injury. Therefore, this case report my help to inform clinicians about the current status of the incidence of acute liver failure of unknown origin during pregnancy. ALF is a life-threatening condition in the absence of preexisting liver disease. Here we report a case of 37-year-old primigravida who presented with insidious acute fulminant hepatic failure
during the third trimester of her pregnancy.