Exploratory Approaches for the Use of Aloe for Covid-19 Treatment: Prevention and Mitigation Effect

Authors

  • Akira Yagi Professor Emeritus of Fukuyama University, Hiroshima Japan; Special Adviser of Japan Aloe Science Association Author
  • A Kabbash Vise-Dean of Faculty of Pharmacy, Professor of Pharmacognosy, Department of Tanta University, Egypt Author
  • BP Yu Professor Emeritus of University of Texas, Health Center, Department of Physiology, San Antonio, the United State Author
  • S Ataka Department of Neurology, Osaka City University, Medical School, Part time Lecturer; The director of Med Cell Clinic, Osaka, Kita-ku, Umeda, Japan Author

DOI:

https://doi.org/10.47363/JDRR/2020(2)118

Keywords:

Exploratory Approaches, Aloe vera Constituents, Gastrointestinal Disorders, COVID-19 Treatment

Abstract

The global coronavirus disease (COVID)-19 pandemic has become a huge threat to humans. Intensive research on the pandemic mechanisms used by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is urgently needed-notably to identify potential drug targets. Clinical studies of patients with COVID-19 have shown that gastrointestinal disorders appear to precede or follow the respiratory symptoms. Here we review exploratory approaches for the use of aloe for COVID treatment, gastrointestinal disorders in patients with COVID-19, suggest hypothetical mechanisms leading to gut symptoms, and discuss the potential consequences of gastrointestinal disorders on the outcome of the disease. Lastly, we discuss the role of the gut microbiota during respiratory viral infections and suggest that targeting food supplement and gut dysbiosis by use of Aloe vera may help to control immunomodulatory effect to the pathogenesis of COVID-19.

Author Biographies

  • Akira Yagi, Professor Emeritus of Fukuyama University, Hiroshima Japan; Special Adviser of Japan Aloe Science Association

    Professor Emeritus of Fukuyama University, Hiroshima Japan; Special Adviser of Japan Aloe Science Association 

  • A Kabbash, Vise-Dean of Faculty of Pharmacy, Professor of Pharmacognosy, Department of Tanta University, Egypt

    Vise-Dean of Faculty of Pharmacy, Professor of Pharmacognosy, Department of Tanta University, Egypt

  • BP Yu, Professor Emeritus of University of Texas, Health Center, Department of Physiology, San Antonio, the United State

    Professor Emeritus of University of Texas, Health Center, Department of Physiology, San Antonio, the United State 

  • S Ataka, Department of Neurology, Osaka City University, Medical School, Part time Lecturer; The director of Med Cell Clinic, Osaka, Kita-ku, Umeda, Japan

    Department of Neurology, Osaka City University, Medical School, Part time Lecturer; The director of Med Cell Clinic, Osaka, Kita-ku, Umeda, Japan

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Published

2020-12-31

Issue

Vol. 2 No. 4 (2020): Volume 2 Issue 4

Section

Articles