Carcinoma of Pyriform Fossa with Mediastinal Metastasis SuccessfullyTreated with Chemoradiotherapy

Abstract

Pyriform sinus is the most common subsite of hypopharyngeal tumors and squamous cell carcinoma sub-type accounts for 70% of all hypopharyngeal cancers [1]. It has the worst prognosis among head and neck cancers. Pyriform sinus is an area that allows tumors to grow silently. Thus, an only a small number of patients present in early stage [2,3]. Distant metastasis from head and neck carcinomas are uncommon. The most common sites of distant metastasis are lung, liver, kidney, and adrenals. Distant metastasis in hypopharyngeal cancer to lung, mediastinum, bone develops in 20-40 % patients within nine months of diagnosis and survival is usually less than one year after metastasis is detected [4]. Here we report a case of squamous cell carcinoma of the pyriform sinus with mediastinal metastasis treated with.