Fatal Outcome in Lung Cancer with Rare Nasal Metastatic Spread:A Clinical Perspective

Abstract

Cutaneous metastases to the nose are a rare manifestation of metastatic squamous cell carcinoma (SCC) of the lung. These metastases can present as either solitary or multiple lesions on the skin, and they may appear either fixed or mobile. Reports of cutaneous metastases from lung cancer specifically affecting the nose occur in 1-12% of cases [1]. In some instances, these cutaneous metastases can be the first indication of an underlying solid epithelial malignancy, often associated with a poor prognosis [2]. When these metastases occur on the nasal tip, they are sometimes referred to as “clown nose” due to their resemblance to a red, fake nose.