A Rare Presentation of Gestational Trophoblastic Neoplasia

Authors

  • Myint Myint Thinn Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar Author
  • Nwe Mar Tun Professor and Head, Department of Obstetrics and Gynecology, University of Medicine (1), Yangon, Myanmar Author
  • Kyi Thar Htun Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar Author
  • Shwe Kyaw Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar Author
  • Htun Lynn Soe Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar Author
  • Thin Myat Myat Shein Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar Author
  • Hsu Myat Mon Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar. Author

DOI:

https://doi.org/10.47363/JTSR/2023(2)123

Keywords:

Gestational , Trophoblastic, Neoplasia

Abstract

Choriocarcinoma is an extremely malignant form of gestational trophoblastic neoplasia which usually metastasize to the lungs, liver and central nervous system. However, metastasis to the gastrointestinal tract is not a common presentation and small bowel choriocarcinoma is an extremely rare occurrence [1]. Metastatic GTN can manifest in 4% of patients after complete mole evacuation and is commonly linked to choriocarcinoma, an invasive and fast-spreading cancer type [2].  It is often difficult to determine the precise histology of choriocarcinoma. The high vascularity of trophoblastic tumors can cause hemorrhage symptoms at the site of metastasis. This, in turn, makes it difficult to obtain tissue biopsy for histology. Moreover, even though surgical intervention may help to reduce the tumour burden as well as control the massive bouts of bleeding before definitive chemotherapy which is the mainstay of treatment, it is sometimes hard for the patient to withstand the effects of double modality treatment due to the situation of the patient. 

Author Biographies

  • Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Nwe Mar Tun, Professor and Head, Department of Obstetrics and Gynecology, University of Medicine (1), Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Kyi Thar Htun, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Shwe Kyaw, Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Htun Lynn Soe, Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Thin Myat Myat Shein, Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

    Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

  • Hsu Myat Mon, Myint Myint Thinn, Senior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar.

    Junior Consultant Gynaeoncologist, Central Women’s Hospital, Yangon, Myanmar

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Published

2025-12-02

Issue

Vol. 2 No. 2 (2023): volume 2 issue 2

Section

Articles