A Review on Tablet in Tablet for Cancer and Use of ArtificialIntelligence (AI)

Abstract

The tablet is the most commonly utilised dosage form because to its stability and high level of acceptance among patients. The film and sugar coatings have a crucial role in enhancing the aesthetic qualities of the tablet, such as colour, texture, mouth feel, and taste masking. Therefore, the coating is a vital component in the tablet formulation. Film and sugar coatings have several drawbacks, with the most significant being the use of aqueous or organic solvents, which can result in toxicity. In 1896, Noyes proposed the compression coating or Tablet in Tablet technology as a solution to this problem. The literature contains significant research reports and patents inputs that have garnered great attention from researchers in the development of Tablet in Tablet dosage form. Furthermore, our attention was directed on the latest progress in methodologies such as one-step dry-coating (OSDrC®) for the analysis of manufacturing properties. Additionally, we discussed the obstacles encountered in the creation of a Tablet in Tablet dosage form for cancer treatment. The present review compiled data on the most recent patent, use of artificial Intelligence for Tablet in Tablet or compression coating.