Identification of Sars Covid-19 Infection among Khartoum StateResident-2021

Abstract

Background: The corona virus disease 2019 (COVID-19) epidemic in China was caused by the extreme acute respiratory syndrome corona virus 2 (SARSCoV-2), December 2019. The clinical manifestations and management of COVID-19 patients remain largely unexplored. However, successful detection is necessary for the diagnosis of SARS-CoV-2 infection. For SARS-CoV-2-infected patients, aiming at evaluating antibodies-based and nucleic acid-based test results. Patients and Method: A cross-sectional retrospective laboratory based study was implemented at Khartoum state 2021. Residents attend to test covid-19
were included by the other hand patients infected with other pneumonic disease were excluded. Blood sample collected from each participant after informed consent and matched inclusion criteria the test proceeded to identify SARS-CoV-2 IgM-IgG antibody test and real-time reverse transcriptase PCR (RT- PCR) for SARS-CoV-2 nucleic acid in COVID-19 suspected respondents. For statistical analysis, version 23 of the Statistical Package for Social Sciences (SPSS) was used. The Crossbat test was used to assess the significance of the discrepancies. The statistical significance was defined at P < 0.05.
Results: By using Polymerase Chain Reaction (PCR), 52 of 100 specimens were reactive for covid-19, whereas 48 were non-reactive. Using a snibe machine for antibody detection, the results showed that 18 specimens were reactive for IgM antibodies, 24 were reactive for IgG antibodies, 30 were reactive for both IgM and IgG antibodies, and 28 were non-reactive.
Conclusion: According to the current study, residents in Khartoum state had a high prevalence of SARS-CoV-2 antibodies