Splenic Rupture Secondary to Amyloidosis: A Rare Case Report

Abstract

Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. Splenic rupture secondary to amyloidosis is an extremely rare complication. While amyloidosis may be systemic or localized, splenic involvement is fairly common (5–10%) and generally asymptomatic. When splenic rupture secondary to localized amyloidosis occurs, it is usually the first manifestation of the disease process. Herein, we report a case of a 57-year-old female who presented a rare case of spontaneous splenic rupture due to localized amyloidosis as an important consideration in the differential of acute abdominal pain.