Clinico Biochemical Profiling of PCOS: Comparative Analysis of Integrated Serum Biomarker Patterns

Abstract

Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, characterized by hormonal imbalances, metabolic abnormalities, and reproductive challenges. PCOS is also the most common endocrine disorder among females of reproductive age worldwide [1]. It is a multifaceted endocrine disorder affecting approximately 8–13% of reproductive-aged women [2]. The disorder significantly impacts various metabolic parameters, notably serum glucose and lipid profiles, and is associated with an increased risk of developing metabolic syndrome, type 2 diabetes, and cardiovascular diseases. The estimation of serum calcium, glucose, and cholesterol levels in PCOS patients provides critical insights into the metabolic derangements associated with the condition, facilitating better clinical management and therapeutic strategies.