Psychosocial Determinants of Bad Quality of Life Among People Living with HIV/AIDS on Antiretroviral Drugs in Kinshasa /DRCongo

Authors

  • Justin Muilu Pila Faculty of Medicine, Simon Kimbangu University (USK), Kinshasa, Democratic Republic of Congo Author
  • Aliocha Nkodila Natuhoyila School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author
  • Yvonne Duagani Masika Department of Psychology, Faculty of Psychology and Educational Sciences, University of Kinshasa (UNIKIN), Republic of Congo Author
  • Germain Manzekele Bin Kitoko Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author
  • Thierry Matonda Ma Nzuzi Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author
  • Hyppolite Situakibanza Nanituma Department of Internal Medicine, Faculty of Medicine, University of Kinshasa (UNIKIN), Republic of Congo Author
  • Guillaume Kiyombo Mbela School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author
  • Gilbert Mananga Lelo Department of Neurology, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author
  • Samuel Mampunza Ma Miezi Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo Author

DOI:

https://doi.org/10.47363/JIDSCR/2024(5)184

Keywords:

HAART, Kinshasa, PLWHA, Psychosocial Determinants, Quality of Life

Abstract

Context and Objective: The search for psychosocial determinants of bad quality of life (Qol) in people living with the human immunodeficiency virus (PLWHA) under Highly active antiretroviral therapy (HAART) constitutes a real public health problem in Kinshasa. Determine the psychosocial factors of bad Qol among PLWHA on antiretrovirals in Kinshasa.

Methods: This was a case control study carried out in Kinshasa from January 15 to April 15, 2021, which included 1082 subjects divided into two groups including 541 PLWHA patients and 541 no-PLWHA. Sampling was non-probability based on matching patients from case to control. Recruitment was carried out first among PLWHA, then matching was done by age and sex considering the sample of PLWHA. The variables of interest were sociodemographic, condom use, psychoactive substance abuse, perceived stress, anxiety-depression, and bad Qol.

Results: The average age of PLWHA was 50.4±10.7 years with a sex ratio of 2.81. A third of PLWHA (32.9%) were married (p< 0,001), 9.2% used condoms (p< 0,001), 68% had a secondary education (p=0,006), 54.3% had an occupation (p=0,005), 54.2% attended independent churches (p=0,033), 52.1% had an average socioeconomic level (p< 0,001), 12.2% consumed alcohol (p< 0,001), 15.3% had a bad Qol. The main determinants of bad quality of life were stage 4 (ORa : 3,06 IC95% : 1,47-7,79), side effects due to HAART (ORa : 1,90 IC95% : 1,04-3,60), perceived stress (ORa : 4,14 IC95% : 1,32-12,94) and anxiety-depression (ORa : 6,88 IC95% : 1,60-9,43).

Conclusion: Bad quality of life is present among PLWHA in Kinshasa. It was linked to stage 4, side effects due to Highly active antiretroviral therapy, perceived stress, anxiety-depression in HIV-positive people.

Author Biographies

  • Justin Muilu Pila, Faculty of Medicine, Simon Kimbangu University (USK), Kinshasa, Democratic Republic of Congo

    Faculty of Medicine, Simon Kimbangu University (USK), Kinshasa, Democratic Republic of Congo

  • Aliocha Nkodila Natuhoyila, School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo


    School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo 

  • Yvonne Duagani Masika, Department of Psychology, Faculty of Psychology and Educational Sciences, University of Kinshasa (UNIKIN), Republic of Congo

    Department of Psychology, Faculty of Psychology and Educational Sciences, University of Kinshasa (UNIKIN), Republic of Congo 

  • Germain Manzekele Bin Kitoko, Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

    Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

  • Thierry Matonda Ma Nzuzi, Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

    Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

  • Hyppolite Situakibanza Nanituma, Department of Internal Medicine, Faculty of Medicine, University of Kinshasa (UNIKIN), Republic of Congo

    Department of Internal Medicine, Faculty of Medicine, University of Kinshasa (UNIKIN), Republic of Congo  

  • Guillaume Kiyombo Mbela, School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

    School of Public Health (ESP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

  • Gilbert Mananga Lelo, Department of Neurology, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

    Department of Neurology, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

  • Samuel Mampunza Ma Miezi, Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

    Department of Psychiatry, Neuro-PsychoPathological Center (CNPP), University of Kinshasa (UNIKIN), Kinshasa, Republic of Congo

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Published

2024-06-20

Issue

Vol. 5 No. 2 (2024): Volume 5 Issue 2

Section

Articles