Skin Delivery and Innovative Carrier’s Effectiveness

Authors

  • Pierfrancesco Morganti Center R&D Nanotechnology Unit, Academy of History of Healthcare Art, Rome Italy, and Dermatological Department, China Medical University, Shenyang, China. Author
  • Giuseppe Fabrizi Dermatological University office, Rome, Italy Author
  • Beatrice Maria Beatrice Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy Author
  • Serena Danti Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy Author
  • Bahareh Azimi Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa Author
  • Alessandro Gagliardini R&D Unit, Texol Srl, Alanna (PE), Italy Author
  • Hong-Duo Chen Key Laboratory of Immunodermatology, National Health Commission, Ministry of Health, the First Hospital of China Medical University, Shenyang, China Author
  • Gianluca Morganti R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, Rome, Italy Author

DOI:

https://doi.org/10.47363/JIMRR/2024(3)132

Keywords:

Skin, Stratum Corneum, Transdermal Delivery System, Percutaneous Adsorption, Non-Woven Tissue, Nicotinamide, Fish Collagen Peptides, Bamboo Tissue

Abstract

The skin serves as the body first protecting barrier against the external attacks of chemicals and microorganisms. On the other hand, it is an obstacle to penetration and transdermal delivery of any substance applied on its surface. Thus, a need to report some news on the skin composition for a better understanding of the transdermal delivery mechanisms of topical products applied on its surface. Therefore, due to the actual increased use of topical drugs, cosmetics, and diet supplement treatments, further feasibility research studies have been carried out to extend the knowledge of the percutaneous absorption ‘rules and means. These studies are retained necessary to control the release through the skin layers of various selected active ingredients, loaded and carried out by different vehicles. The paper will focus on the effectiveness of innovative tissue carriers that, are able to deliver active ingredients throughout the skin layers, are made by a very low consumption of water, and are free of chemicals also. In conclusion, these novel eco-sustainable carriers, resulting skin- and environmentally friendly, might be used as innovative vehicles in substitution of the normal emulsions that, made by the use of
preservatives, emulsifiers, fragrances, and other chemicals may often cause allergic and/or sensitization phenomena, consuming a great quantity of water also. 

Author Biographies

  • Pierfrancesco Morganti, Center R&D Nanotechnology Unit, Academy of History of Healthcare Art, Rome Italy, and Dermatological Department, China Medical University, Shenyang, China.

    Center R&D Nanotechnology Unit, Academy of History of Healthcare Art, Rome Italy, and Dermatological Department, China Medical University, Shenyang, China.

  • Giuseppe Fabrizi, Dermatological University office, Rome, Italy


    Dermatological University office, Rome, Italy 

  • Beatrice Maria Beatrice, Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy

    Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy 

  • Serena Danti, Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy

    Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy

  • Bahareh Azimi, Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa


    Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa 

  • Alessandro Gagliardini, R&D Unit, Texol Srl, Alanna (PE), Italy


    R&D Unit, Texol Srl, Alanna (PE), Italy

  • Hong-Duo Chen, Key Laboratory of Immunodermatology, National Health Commission, Ministry of Health, the First Hospital of China Medical University, Shenyang, China


    Key Laboratory of Immunodermatology, National Health Commission, Ministry of Health, the First Hospital of China Medical University, Shenyang, China 

  • Gianluca Morganti, R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, Rome, Italy

    R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, Rome, Italy 

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Published

2024-07-08