Langerhans Cell Histiocytosis of the Temporal Bone in a Childwith Central Diabetes Insipidus

Authors

  • Mariam LAGRINE Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Youness LABANI Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Karima EL FAKIRI ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Noureddine RADA ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Ghizlane DRAISS ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Hassan NOURI ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Abdelaziz RAJI ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author
  • Mohammed BOUSKRAOUI ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco Author

DOI:

https://doi.org/10.47363/JPRRR/2020(2)111

Keywords:

Langerhans cell histiocytosis, diabetes insipidus, temporal bone

Abstract

Langerhans cell histiocytosis is a rare clonal disease defined by an accumulation of dendritic cells with Langerhans cell immunological properties within different organs of the body. We intend to describe a new case of Langerhans cell histiocytosis of the temporal bone in a child with central diabetes insipidus. The child presented the polyuria-polydipsia syndrome for 6 months with Chronic bilateral otorrhea. On physical examination,there were bilateral retroauricular redness and induration. The otoscopy visualized inflammatory polyps filling all of the right and left external ear canal. Biological exploration confirmed the
central diabetes insipidus. Magnetic resonance imaging of the brain showed the presence of pituitary infiltration. Computed tomography showed osseous lysis of the temporal bone bilaterally. A retroauricular biopsy was performed under general anesthesia. Histological and immunohistochemical evaluation confirmed the diagnosis of Langerhans cell histiocytosis.

Author Biographies

  • Mariam LAGRINE, Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco

    Mariam Lagrine, Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco.

  • Youness LABANI, Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco

    Mariam Lagrine, Pediatric A Departement, Mohammed VI University Hospital Center, Marrakech, Morocco.

  • Karima EL FAKIRI, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco


    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

  • Noureddine RADA, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

  • Ghizlane DRAISS, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

  • Hassan NOURI, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

  • Abdelaziz RAJI, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

  • Mohammed BOUSKRAOUI, ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

    ENT-HNS Department, Mohammed VI University Hospital Center, Marrakech, Morocco

Downloads

Published

2020-10-14

Issue

Vol. 2 No. 4 (2020): Volume 2 Issue 4

Section

Articles