Analysis of the Advantages and Limitations of Liquid Biopsy: A Literature Review

Abstract

Considering the high morbidity and mortality associated with neoplasms and the need for more effective diagnostic methods and less invasive, a biopsy liquid if This technique stands out as a promising tool for the early diagnosis and monitoring of cancers. The aim is to critically analyze the advantages and limitations of this technique in the context of general surgery, addressing... your impact clinical, effectiveness and you challenge to your wide implementation. To Therefore, a systematic literature review was conducted, focusing on recent studies on the use of circulating biomarkers, such as ctDNA and Circulating Tumor Cells (CTCs). in detection of cancers. You results show what, although the biopsy liquid While liquid biopsy offers advantages such as less invasiveness and the ability to monitor tumor progression over time, significant challenges remain, including reduced sensitivity in early stages of the disease, a lack of standardization in collection and analysis methods, and the high costs of sequencing technologies. In conclusion, despite its limitations, liquid biopsy has the potential to transform cancer diagnosis and treatment in clinical practice, especially when integrated with traditional methods, provided that sequencing technologies advance and standardized protocols are established.