Authors
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Seyedehnarges Tabatabaee
Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Author
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Mostafa Almasi-Dooghaee
Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran, Iran
Author
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Somaye Farhoodi
Neurology Department, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Author
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Tara Khoeini
Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Author
Keywords:
Cerebrospinal Fluid Leak, Hydrocephalus, Normal Pressure, Cerebrospinal Fluid Rhinorrhea, Spinal Tap
Abstract
Normal Pressure Hydrocephalus (NPH) is a reversible cause of dementia that often responds to Cerebrospinal Fluid (CSF) drainage. Spontaneous CSF
leakage is rare in this setting. We report a 79-year-old man with urinary incontinence, gait disturbance, and cognitive decline, diagnosed with probable NPH. Serial lumbar punctures led to marked improvement. During a treatment delay due to the COVID-19 pandemic, he developed spontaneous CSF rhinorrhea, which was followed by further symptomatic relief. This case suggests that spontaneous CSF leakage may temporarily replicate the therapeutic effects of CSF drainage, offering insight into symptom fluctuation and potential diagnostic markers in NPH.
Author Biographies
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Seyedehnarges Tabatabaee, Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Seyedehnarges Tabatabaee, Neurology department, Firoozgar Hospital, Valadi St, Valiasr Ave, Tehran, Iran.
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Mostafa Almasi-Dooghaee, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran, Iran
Mostafa Almasi-Dooghaee, Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
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Somaye Farhoodi, Neurology Department, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Somaye Farhoodi, Neurology Department, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
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Tara Khoeini, Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Tara Khoeini, Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
