Challenges and Limitations of Personalized Cancer Vaccines

Abstract

Personalized cancer vaccines represent a promising frontier in
oncology, offering the potential for highly targeted and effective
treatments. However, this innovative approach faces significant
challenges and limitations, including tumor heterogeneity rapid
cellular mutation manufacturing complexity, immune system
evasion, identifying suitable antigens, and cost [1,2]. Furthermore,
limited long-term efficacy data, scalability, and regulatory hurdles
create serious obstacles to applying personalized cancer vaccines