Bisalbuminemias Caused by Betalactamine Antibiotic and Syndrome Nephrotic: Case Report

Abstract

Bisalbuminemia is a rare qualitative anomaly, it is hereditary or acquired, transient and physiopathology remains a little unknown, characterized by the occurrence of bicuspid electrophoretic pattern in the albumin fraction detected on serum electrophoresis. These albumin mutants also called alloalbumins either have decreased mobility (slow type variants) or increased electrophoretic mobility (fast type variants).

Case Presentation: The study presents 6 cases of bisalbuminemias collected on 2083 serum protein electrophoresis carried out at the laboratory of biochemistry of CHU Ibn Rochd of Casablanca over a spread period of one year (2018).

Conclusions: The results of serum protein electrophoresis of 6 reported cases showed bisalbuminemias which are all of acquired and transient type, of which 3 cases are related to the drug intake of betalactamine antibiotic and the other 3 are related to the syndrome nephrotic.