Cave CANEM! Management of in “CID” ENTAL Sepsis

Abstract

Background: The pathogenesis of sepsis is linked to abnormalities in the coagulation process, which can progress to disseminated intravascular coagulation (DIC). This complication is triggered by an abnormal inflammatory response to an infectious agent which leads to the massive production of inflammatory mediators, increasing exposure to pro-coagulant factors and decreasing the expression of anticoagulant factors, such as antithrombin.