Mad Honey (Grayanotoxin) Poisoning Presenting with Severe Hypotension and Syncope: A Case Report

Abstract

Mad honey poisoning is a relatively common clinical condition in regions where Rhododendron species are widespread, particularly in the Black Sea region of Turkey. It is caused by grayanotoxins found in certain types of honey and typically presents with cardiovascular and neurological symptoms such as bradycardia, hypotension, dizziness, and syncope.

We present a 46-year-old male patient admitted to the emergency department with dizziness and syncope following ingestion of honey obtained from the Black Sea region. On admission, he had severe hypotension and bradycardia. Despite initial treatment with intravenous fluids and atropine, vasopressor support was required. The patient responded well to treatment and was discharged without complications.

This case highlights the importance of considering mad honey poisoning in patients presenting with unexplained bradycardia and hypotension, especially in endemic areas.