Sudden Onset of SJS in 14yr Olg Girl on Taking Antibiotic Drug– A Case Report

Abstract

Each year many patients are hospitalized due to adverse drug reactions. Amoxicillin is a broad spectrum , bactericidal, beta lactum antibiotic, commonly used to combat various infections. Pencillin group of drugs are known to cause cutaneous drug eruption especially in pediatric population. Paracetamol is used as antipyretic and analgesic Steven Johnson syndrome is an acute, self limited disease, presenting as severe mucosal erosions with wide spread erythematous, cutaneous macules. Majority of cases are drug induced affecting oral and peri- oral region. Aim of the article is to present a case of steven Johnson syndrome primary to drug therapy amoxicillin and paracetamol. A 14 years female patient was admitted in hospital with a chief complaints of blisters over tongue, lips, difficult in swallowing, patient was dehydrated and fever since 5days. The reaction was evoked after consumption of tab amoxicillin, and paracetamol. She was treated with corticosteroids, local anesthetic, antiseptic, antifungal, iv fluids. Health care provider must be carefully regarding the adverse effect of drug especially Steven Johnson syndrome which is a potentially fatal condition. The case being reported to emphasize the need for pharmacovigillance in order to motivate adverse drug reaction reporting so as to gather more data regarding adverse drug reaction.