Pregnancy after Fertility-Sparing Treatment for Cervical Cancer in Young Women: A Case Presentation

Abstract

Introduction: Cervical cancer remains a major global public health challenge despite being largely preventable. Over the past three decades, fertility-sparing surgery has become an increasingly important treatment option for selected patients with early-stage cervical cancer, offering preservation of fertility as an alternative to radical hysterectomy. We present a case report of a young woman who achieved a successful pregnancy after fertility-sparing treatment for cervical cancer.

Case Presentation: A 38-year-old nulliparous woman with a history of recurrent high-grade Cervical Intraepithelial Neoplasia (CIN III) underwent repeat cervical excision after persistent HSIL, which revealed FIGO IA1 microinvasive squamous cell carcinoma without lymphovascular invasion. Following multidisciplinary evaluation, she underwent fertility-sparing simple trachelectomy with negative surgical margins. After one unsuccessful IVF pregnancy, she conceived spontaneously and delivered a healthy male infant by cesarean section at 36 weeks’ gestation. At follow-up, she remained disease-free with normal cytology, colposcopy, and negative HPV testing.

Conclusion: Fertility-sparing treatment can provide excellent oncologic and reproductive outcomes in carefully selected patients with early-stage cervical cancer. This case emphasizes the importance of individualized, multidisciplinary management to balance oncologic safety with fertility preservation and achieve successful pregnancy after treatment.