Cognitive Decline in an Elderly Patient with a History of Pernicious Anemia: an Unexpected Finding

Authors

  • Daniela Zermeño-Napolitano Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico Author
  • Haiko Nellen-Hummel Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico Author
  • Rodrigo Villaseñor-Echavarri Department of Internal Medicine, The American British Cowdray Medical Center, Mexico Vasco de Quiroga 154, Cuajimalpa, 05348, Mexico City, Mexico Author

DOI:

https://doi.org/10.47363/JIMRR/2026(5)150

Keywords:

Pernicious Anemia

Abstract

An 82-year-old woman presented with a two-week history of progressive cognitive decline. Her past medical history included wellcontrolled hypertension and pernicious anemia diagnosed six months earlier, confirmed by positive anti-parietal cell antibodies and treated with cyanocobalamin, currently on monthly maintenance. She reported generalized weakness, slowed thinking, memory loss, and language difficulties characterized by word-finding pauses and slow speech. She denied headache, urinary incontinence, and paresthesias.

Author Biographies

  • Daniela Zermeño-Napolitano, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico

    Daniela Zermeño-Napolitano, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico

  • Haiko Nellen-Hummel, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico

    Haiko Nellen-Hummel, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico City, Mexico

  • Rodrigo Villaseñor-Echavarri, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico Vasco de Quiroga 154, Cuajimalpa, 05348, Mexico City, Mexico

    Rodrigo Villaseñor-Echavarri MD, Department of Internal Medicine, The American British Cowdray Medical Center, Mexico Vasco de Quiroga 154, Cuajimalpa, 05348, Mexico City, Mexico.

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Published

2026-04-13

Issue

Vol. 5 No. 2 (2026): Volume 5 Issue 2

Section

Articles