Bio-Nanowound Dressing: A Natural Breakthrough for Burns and Chronic Wounds

Abstract

This lecture focuses on the production of a 100% natural bio-nanofibrous wound dressing fabricated from natural nanopolymeric fibers with dimensions ranging from 50–100 nm and featuring an ultra-high porosity of 150–200 nm. The dressing is intended for clinical application in the treatment of burns and chronic wounds, accelerating the healing process. In parallel, silver nanoparticles are produced and applied for sterilizing burns and wounds prior to using the dressing. The bio-nanowound dressing exhibits distinctive advantages: it is semi-permeable, allowing the exchange of oxygen and water vapor while simultaneously acting as a natural barrier against bacterial penetration. Moreover, it is easy to use, replaceable, and reusable after sterilization with locally synthesized silver nanoparticles. This innovative dressing can be applied in multiple medical cases, including skin burns, skin graft donor and recipient sites, keloids, diabetic ulcers, perforated foot disease, contaminated surgical wounds, pressure ulcers, injuries following thermal cauterization or cryotherapy, and even in dental applications, such as regenerating odontogenic cells, endodontic treatments, and preventing post-extraction alveolar bone loss. This product represents the first of its kind in Syria, rivaling globally manufactured dressings, while being fully natural, flexible, tear-resistant, user-friendly, and cost effective. It can be manufactured in various sizes 
tailored to wound or burn dimensions. Importantly, it contributes significantly to improving patients’ quality of life by accelerating wound healing and reducing healthcare costs.