The Effect of Covid-19 Astrazeneca Vaccines on Some Coagulation Profile (Pt, Aptt) Among Sudanese Two Dose Vaccinated

Authors

  • Amged Hussein Abdelrhman Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Ahmed Hosham Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Duaa Sala Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Marwan Adel Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Nadeen wahbi Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Sara Abdelrahim Department of Hematology and Immunohematology, Elrazi University, Sudan Author
  • Waad Abdullah Department of Hematology and Immunohematology, Elrazi University, Sudan Author

DOI:

https://doi.org/10.47363/JMHC/2022(4)204

Keywords:

Covid-19, Astrazeneca, Coagulation

Abstract

Background: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to humanity in a century. It is widely believed that pracademic normalcy will never return until a safe and effective vaccine strategy becomes available and a global vaccination programmed is implemented successfully.

Design: This descriptive (case – control) analytical study carried out in Sudanese from June to December 2021 to determine the effect coagulation profile between AstraZeneca vaccinated and non- vaccinated.

Materials and Methods: whole blood sample collected in Trisodium Citrate anticoagulant from 500 vaccinated case and 500 control non vaccinated, PPP prepared and the tests was carried out using coagulometer, Objective: This study aimed to evaluate some coagulation profile (PT, APTT and INR) among Sudanese AstraZeneca vaccinated.

Results: The result show significant different between case and control in (PT, APTT and INR) and significant different between male and female in (PT, APTT). Conclusion: This study concluded that the statistically significant different in (PT, APTT and INR) between vaccinated.

Author Biographies

  • Amged Hussein Abdelrhman, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Ahmed Hosham, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Duaa Sala, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Marwan Adel, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Nadeen wahbi , Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Sara Abdelrahim, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

  • Waad Abdullah, Department of Hematology and Immunohematology, Elrazi University, Sudan

    Department of Hematology and Immunohematology, Elrazi University, Sudan 

Downloads

Published

2022-07-21

Issue

Vol. 4 No. 4 (2022): Volume 4 Issue 4

Section

Articles