A Review of Sars-Cov-2 Infection in Pregnancy: What We Know So Far

Abstract

Coronavirus infection (COVID-19) in pregnancy is highly relevant due to the impact on maternal and fetal health, it is caused by SARS-CoV-2, which has a high morbidity and mortality rate worldwide. It is important to evaluate pregnant patients who are identified as suspicious, to make an accurate and timely diagnosis, to implement correct follow-up and adequate therapeutic management to reduce associated complications and adverse perinatal outcomes.

Objective: Execute a detailed and updated review of the causal agent, pathophysiology, diagnostic methods, treatment, maternal and fetal repercussions, via of delivery and whether there is evidence of vertical transmission.

Method: A search of literature published in English and Spanish was carried out in databases such as PubMed / MEDLINE, MDconsult, HSTAT, Internet Grateful Med, using the keywords: Coronavirus, pregnancy, SARS-CoV-2, treatment, vertical transmission. From the information obtained, 88 articles were selected, which were classified and used as support to do this review.

Results: Studies and available evidence, reviews, and recommended guidelines for the evaluation of patients with COVID-19 are discussed, mainly those that provide valuable data regarding the diagnosis, monitoring and management of this infection.

Conclusion: Information is limited and much remains to be studied about vertical transmission and perinatal outcomes. There is no evidence to support that pregnancy increases the susceptibility to get COVID-19. More studies are necessary to know the behavior of the infection in pregnancy, for a better approach, diagnosis and treatment.