Psychiatric Side Effects Caused by Tirzepatide

Authors

  • Melekhin Alexey Igorevich Candidate of Psychological Sciences, Associate Professor, Clinical Psychologist of the Highest Qualification Category, Stolypin Humanitarian Institute, Moscow, Russia Author

DOI:

https://doi.org/10.47363/JNRRR/2026(8)245

Keywords:

Eating Disorders, Obesity, Tirzepatide

Abstract

The work reveals the issue of neuropsychiatric (psychological) safety of GLP-1 receptor agonists of tirzapatide used for the treatment of type 2 diabetes mellitus, obesity and eating disorders. The complex advantages of tirzepatide in relation to metabolic and psychological health are highlighted, making it a safe and effective remedy for patients with severe obesity (BMI>30), including night eating syndrome. The profile of psychiatric side effects when taking tirzepatide is described. The emphasis is placed on the fact that a number of patients use these drugs as a form of corrective (cleansing) behavior. In this regard, when prescribing these drugs, comorbid mental disorders in the patient and early maladaptive patterns should be taken into account.

Author Biography

  • Melekhin Alexey Igorevich, Candidate of Psychological Sciences, Associate Professor, Clinical Psychologist of the Highest Qualification Category, Stolypin Humanitarian Institute, Moscow, Russia

    Candidate of Psychological Sciences, Associate Professor, Clinical Psychologist of the Highest Qualification Category, Stolypin Humanitarian Institute, Moscow, Russia

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Published

2026-02-04

Issue

Vol. 8 No. 2 (2026): Volume 8 Issue 2

Section

Articles