RBPs Related to The Metastatic Process of Hepatocellular Carcinoma

Abstract

Hepatocellular carcinoma metastasis is often the leading cause of treatment failure in hepatocellular carcinoma. It is now recognized that metastasis is a complex process involving multiple factors and that aberrant expression or dysfunction of RBP, leading to an imbalance in the expression of proto-oncogenes and oncogenes, is inextricably involved in the process of tumor metastasis, which will be discussed in the review. In this review, we will discuss the mechanism and role of RBP in the metastasis of hepatocellular carcinoma. Basic regulatory strategies of RBP most RBPs contain one or more conventional RBDs, which recognize and bind specific sequences in RNAs in order to play their roles. The RBDs, together with some repetitive sequences, form the basic modules, which, through various combinations and permutations, enable the RBPs to accurately search for RNAs for recognition in the cell and participate in regulating RNAs.