Effect of TLR4 on Apoptosis of HL-7702 Hepatocytes throughPI3K/AKT /GSK3β Pathway

Authors

  • Wu Chunming Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China Author
  • Ouyang Chin Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China Author
  • Wang Xiaodong Zhejiang Key Laboratory of Precision Diagnosis, Treatment and Translation of Chronic Liver Disease Critically Illness, The First Hospital of Wenzhou Medical University, Wenzhou, China Author
  • Liu Sanhai Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China Author
  • Zhao Anjing Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China Author

DOI:

https://doi.org/10.47363/JTMCM/2025(3)118

Keywords:

Apoptosis Hepatocyte, Signal Pathway, Toll-like 4 Receptor, PI3K/AKT/GSK3β

Abstract

To investigate whether toll-like receptor (TLR4) regulates apoptosis through PI3K/AKT/GSK3β signaling pathway in human HL-7702 hepatocytes and to investigate its regulatory mechanism

Author Biographies

  • Wu Chunming, Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

    Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

  • Ouyang Chin, Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

    Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

  • Wang Xiaodong, Zhejiang Key Laboratory of Precision Diagnosis, Treatment and Translation of Chronic Liver Disease Critically Illness, The First Hospital of Wenzhou Medical University, Wenzhou, China

    Zhejiang Key Laboratory of Precision Diagnosis, Treatment and Translation of Chronic Liver Disease Critically Illness, The First Hospital of Wenzhou Medical
    University, Wenzhou, China

  • Liu Sanhai, Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

    Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

  • Zhao Anjing, Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

    Department of Infection, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, China

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Published

2025-01-20

Issue

Vol. 3 No. 1 (2025): Volume 3 Issue 1

Section

Articles