Optogenetic Cardiac Pacing and Its Applications

Authors

  • Airong Li Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown MA, USA Author
  • Rudolph E Tanzi Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown MA, USA Author

DOI:

https://doi.org/10.47363/JCRRR/2021(2)134

Keywords:

Cardiac Pacing, Optogenetic, Optogenetic Cardiac

Abstract

Optogenetics combines the biological techniques of optics and genetics and uses light to control the activities of living tissues such as neurons and heart. 
Optogenetic actuators including channelrhodopsin (ChR), halorhodopsin (NpHR), and archaerhodopsin specifically provide for neuronal or cardiac 
controls. The clinical translation of cardiac optogenetics will include human and larger mammalian animal model applications and ultimately optogenetics may have the power to restore normal heart rhythm.

Author Biographies

  • Airong Li, Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown MA, USA

    Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown 
    MA, USA

  • Rudolph E Tanzi, Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown MA, USA

    Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown 
    MA, USA

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Published

2021-01-13

Issue

Vol. 2 No. 1 (2021): volume 2 Issue 1

Section

Articles