Quantitative Analysis of Cyclosieversioside F from Astragalus Pterocephalus

Authors

  • Manzura Agzamova S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan. Author
  • Fatih Goger Department of Pharmaceutical Botany, Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey. Author
  • Gülmira Ozek Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey. Author
  • Abdulaziz Janibekov S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan. Author

DOI:

https://doi.org/10.47363/JCIA/2024(3)130

Keywords:

Cyclosieversioside F, Astragaloside IV, Astragalus Pterocephalus, Tragacantha Pterocephala, Fabaceae, Cardioprotector, Chromatography HPLC, ELSD, TLC

Abstract

Astragalus pterocephalus Bunge growing in Uzbekistan are a source of triterpene glycosides. The main triterpene glycoside, is a cycloartane type -
cyclosieversioside F (astragaloside IV). To obtain a biologically active compound cyclosieversioside F with 95% purity, a proposed method involves extraction with ethanol. The optimal conditions for the isolation and separation of the amount of extract have been tried to obtain cyclosieversioside F. Quantitative analysis of the glycoside was carried out by high-pressure liquid chromatography, HPLC-ELSD.

Author Biographies

  • Manzura Agzamova, S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan.

    Manzura Agzamova, S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan.

  • Fatih Goger, Department of Pharmaceutical Botany, Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

    Fatih Goger, Department of Pharmaceutical Botany, Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

  • Gülmira Ozek, Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.

    Gülmira Ozek, Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.

  • Abdulaziz Janibekov, S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan.

    Abdulaziz Janibekov, S Yu Yunusov Institute of the Chemistry of Plant Substances Tashkent, Uzbekistan.

Downloads

Published

2024-03-20

Issue

Vol. 3 No. 2 (2024): Volume 3 Issue 2

Section

Articles