Investigation of Antifungal Activity of Moringa Oleifera and Hyphaene Thebaica Extracts

Authors

  • Omer Mohammed Department of Pharmaceutical Chemistry, Faculty of Pharmacy,Managil University for Science and Technology, Sudan Author
  • Nizar Sirag Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, Tabuk University, Saudi Arabia Author
  • Assad Khalid Substance Abuse Research Center, Jazan University, Saudi Arabia Author
  • Husham E Homeida Faculty of Dentistry, Jazan University, Saudi Arabia Author

DOI:

https://doi.org/10.47363/JIDSCR/2024(5)188

Keywords:

Moringa Oleifera, Hyphaene Thebaica, In Vitro Antifungal Activity, Minimum Inhibitory Concentration

Abstract

Background: Plants may provide a promising source of bioactive compounds that could be used to control infectious diseases.

Objective: This study was undertaken to explore antifungal activities of two plant extracts.

Methods: Antifungal activity was determined by the aid of disc diffusion method against three references fungal strains, using different dilution (5, 25,
50, 100, 250 μg/ml).

Results: Inhibition zone of the extracts was compared with different standards (Nystatin and Griseofulvin). Our study illustrated the occurrences of antimicrobial efficacy.

Conclusion: The results of the present study have shown that Moringa oleifera and Hyphaene thebaica possess a promising antifungal activity. Hence further surveys prerequisite to isolate the effective constituents responsible for this activity.

Author Biographies

  • Omer Mohammed, Department of Pharmaceutical Chemistry, Faculty of Pharmacy,Managil University for Science and Technology, Sudan

    Department of Pharmaceutical Chemistry, Faculty of Pharmacy,Managil University for Science and Technology, Sudan 

  • Nizar Sirag, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, Tabuk University, Saudi Arabia

    Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, Tabuk University, Saudi Arabia

  • Assad Khalid, Substance Abuse Research Center, Jazan University, Saudi Arabia

    Substance Abuse Research Center, Jazan University, Saudi Arabia

  • Husham E Homeida, Faculty of Dentistry, Jazan University, Saudi Arabia

    Faculty of Dentistry, Jazan University, Saudi Arabia

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Published

2024-03-05

Issue

Vol. 5 No. 1 (2024): Volume 5 Issue 1

Section

Articles