Laboratory evaluation of Capilia TB-Neo and BD MGITTM TBc ID antigen test to identify Mycobacterium tuberculosis complex from BD MGIT Positive Cultures

Authors

  • Mamello B Motsei Centre for Tuberculosis, National TB Reference Laboratory, WHO TB Supranational Reference Laboratory Network, National Institute for Communicable Diseases (NICD) a division of the National Health Laboratory Services (NHLS), Sandringham, Johannesburg, South Africa. Author

DOI:

https://doi.org/10.47363/JJCMR/2025(5)212

Keywords:

Mycobacterium Tuberculosis, Non-Tuberculous Mycobacteria, Antigen, Immuno-Chromatographic Tests

Abstract

Rapid identification of Mycobacterium Tuberculosis Complex (MTBC) from cultures is essential for TB control. Capilia TB-Neo and BD TBc antigen
tests were evaluated on 64 MGIT-positive cultures. Both showed high concordance (96.8%), with Capilia detecting two additional MTBC-positive cases confirmed by line probe assay, indicating slightly superior performance.

Author Biography

  • Mamello B Motsei, Centre for Tuberculosis, National TB Reference Laboratory, WHO TB Supranational Reference Laboratory Network, National Institute for Communicable Diseases (NICD) a division of the National Health Laboratory Services (NHLS), Sandringham, Johannesburg, South Africa.

    Mamello B Motsei, Centre for Tuberculosis, National TB Reference Laboratory, WHO TB Supranational Reference Laboratory Network, National Institute for Communicable Diseases (NICD) a division of the National Health Laboratory Services (NHLS), Sandringham, Johannesburg, South Africa.

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Published

2025-09-09

Issue

Vol. 5 No. 5 (2025): Volume 5 Issue 5

Section

Articles